Brain abscess caused by Trueperella bernardiae in a child

James Pan, Allen L. Ho, Arjun V. Pendharkar, Eric S. Sussman, May Casazza, Samuel H. Cheshier, Gerald A. Grant

Date of publication: 29-Mar-2019

Background:Recurrent intracranial abscesses secondary to refractory otitis media present a challenge which demands multidisciplinary collaboration.

Subgaleal and brain abscesses due to Salmonella enteritidis following craniotomy for giant cell glioblastoma multiforme: A case report and literature review

Ali Akhaddar, Walter Hall, Mohammed Boucetta

Date of publication: 26-Mar-2019

Background:Cranial surgical site infections due to Salmonella species are rarely reported. Only eight cases of Salmonella enteritidis infection following intracranial surgery for brain tumor have been reported to date. We describe a unique case of both subgaleal and brain abscesses caused by S. enteritidis following craniotomy for a parafalcine giant cell glioblastoma multiforme. A literature review of the previously published cases is also provided.

Bridging the gap: Spinal cord fusion as a treatment of chronic spinal cord injury

Xiaoping Ren, C-Yoon Kim, Sergio Canavero

Date of publication: 26-Mar-2019


Despite decades of animal experimentation, human translation with cell grafts, conduits, and other strategies has failed to cure patients with chronic spinal cord injury (SCI). Recent data show that motor deficits due to spinal cord transection in animal models can be reversed by local application of fusogens, such as Polyethylene glycol (PEG). Results proved superior at short term over all other treatments deployed in animal studies, opening the way to human trials. In particular, removal of the injured spinal cord segment followed by PEG fusion of the two ends along with vertebral osteotomy to shorten the spine holds the promise for a cure in many cases.

Reconstruction of the spinal cord of spinal transected dogs with polyethylene glycol

Shuai Ren, Zehan Liu, C. Yoon Kim, Kuang Fu, Qiong Wu, Liting Hou, Linlin Sun, Jian Zhang, Qing Miao, Jin Kim, Vincenzo Bonicalzi, Xiangchen Guan, Mingzhe Zhang, Weihua Zhang, Junfeng Xu, Sergio Canavero, Xiaoping Ren

Date of publication: 26-Mar-2019

Background: Our study shows that a membrane sealant/fiber fusogen polyethylene glycol (PEG) applied immediately on a sharp section of the spinal cord can mend the cord and lead to exceptional levels of motor recovery, with some animals almost normal.

Extradural en-plaque spinal lipomatous meningioma: A case report and literature review

Sayoa Alvarez de Eulate-Beramendi, Kelvin Manuel Piña-Batista, Juan Carlos Rial-Basalo

Date of publication: 26-Mar-2019

Background: Extradural spinal meningiomas are rare, and few appear as lipomatous meningiomas in an “en-plaque” form. The transitional fibroblastic subtype, with lipid accumulation within the tumoral cells, is typically more aggressive and surgically challenging to resect.

Bilateral cervical facet dislocations at two adjacent levels: A case report

Ajmal Zemmar, Hanbing Zhou, Vincent Ye, Jason Schewchuk, David Volders, Nicolas Dea

Date of publication: 26-Mar-2019

Background: Cervical facet dislocations are rare in patients sustaining traumatic subaxial injuries. They occur due to hyperflexion-distraction and can occur unilaterally or bilaterally resulting in significant spinal instability. Bilateral facet dislocations at one level are less common than unilateral dislocations, while bilateral facet dislocations at adjacent spinal levels have only been reported twice in literature.

Endovascular treatment of idiopathic intracranial hypertension caused by multiple venous sinus stenoses

Yudai Morisaki, Ichiro Nakagawa, Koji Omoto, Takeshi Wada, Kimihiko Kichikawa, Hiroyuki Nakase

Date of publication: 26-Mar-2019

Background: Idiopathic intracranial hypertension (IIH) shows symptoms by elevating intracranial pressure. Although sinus stenosis has been detected in many patients with IIH, the role of sinus stenosis in IIH remains obscure. Endovascular treatment for IIH due to transverse sinus stenosis has been frequently documented; however, IIH due to multiple sinus stenoses including the superior sagittal sinus (SSS) is rare. Here, we report a case of IIH due to multiple sinus stenoses treated by sinus stenting.

QEVO® - A new digital endoscopic microinspection tool - A cadaveric study and first clinical experiences (case series)

Karl-Michael Schebesch, Alexander Brawanski, Ernst R. Tamm, Thomas S. Kühnel, Julius Höhne

Date of publication: 26-Mar-2019

Background: The use of endoscopes in neurosurgery is well established, but the integration of a full high definition signaling, 45° angled endoscopic tool into a digital surgical microscope, is new. We report our first experiences in a cadaveric study and a clinical case series using the new microinspection tool QEVO® that serves as a plug-in feature for the recently launched KINEVO 900 digital visualization platform (CARL ZEISS MEDITEC, Oberkochen, Germany). For illustration purposes, we offer video footage.

When to stop anticoagulation, anti-platelet aggregates, and non-steroidal anti-inflammatories (NSAIDs) prior to spine surgery

Nancy E. Epstein

Date of publication: 26-Mar-2019

Background: Based upon a select review of the literature, in my opinion, spine surgeons, not just our medical/cardiological colleagues, need to know when to stop anticoagulant, anti-platelet aggregates, and non-steroidal anti-inflammatory (NSAIDs) medications prior to spine surgery to avoid perioperative bleeding complications.

Avoiding inappropriate spine surgery in a patient with major cardiac comorbidities

Nancy E. Epstein

Date of publication: 26-Mar-2019

Background: We as spine surgeons increasingly need to carefully screen our own patients for major medical/cardiac comorbidities to determine if they are candidates for spine surgery. Our medical/cardiac colleagues rarely understand how long anti-platelet aggregates and non-steroidal anti-inflammatories (NSAIDs) have to be stopped prior to spine operaeitons, and when it is safe for them to be reinstated.