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Javier Goland, Luis Domitrovic, Gustavo Doroszuk, Silvia Garbugino, Paula Ypa
  1. Neurointervencionismo, Hospital El Cruce, Florencio Varela, Buenos Aires,
  2. Neurocirugía, Hospital de Clinicas, UBA, Buenos Aires, Argentina,
  3. Radiología, Hospital Vithas Parque San Antonio, Málaga, España.

Correspondence Address:
Javier Goland
Neurocirugía, Hospital de Clinicas, UBA, Buenos Aires, Argentina,

DOI:10.25259/SNI_410_2019

Copyright: © 2019 Surgical Neurology International This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

How to cite this article: Javier Goland, Luis Domitrovic, Gustavo Doroszuk, Silvia Garbugino, Paula Ypa. Distal radial approach for neurointerventional diagnosis and therapy. 01-Nov-2019;10:211

How to cite this URL: Javier Goland, Luis Domitrovic, Gustavo Doroszuk, Silvia Garbugino, Paula Ypa. Distal radial approach for neurointerventional diagnosis and therapy. 01-Nov-2019;10:211. Available from: http://surgicalneurologyint.com/surgicalint-articles/9733/

Date of Submission
26-Aug-2019

Date of Acceptance
09-Oct-2019

Date of Web Publication
01-Nov-2019

Abstract

Background: The transradial approach results in fewer complications at the puncture site, lower hospital costs, and greater comfort for patients. The distal transradial approach (dTRA) adds some benefits over the conventional radial approach. The objective is to describe initial experience with distal radial approach technique and the results obtained for neuroendovascular diagnostic and therapeutic procedures.

Methods: Description of distal radial approach technique and obtained data from the first 3 months experience using this approach as the first choice for neuroendovascular procedures in two neuroendovascular centers.

Results: Of the total of 94 procedures performed during 3 months, 67 were diagnostic and 27 were therapeutic. Eleven (16%) of the diagnostic procedures were performed through the dTRA. Of the 27 embolizations, eight (30%) were done using this approach. Every distal radial approach that was performed for diagnosis and therapeutics was successful.

Conclusion: Puncture of the radial artery within the anatomical snuffbox is a radial approach variation option for diagnostic and therapeutic neuroendovascular procedures.

Keywords: Approach, Distal radial, Neurointerventional

BACKGROUND

The transradial approach has emerged as a neurointerventional option for the diagnosis and treatment of cerebral aneurysms.[ 3 - 6 , 9 , 10 ] Comparative studies of patients who underwent radial or femoral cardiac catheterization have shown that the transradial approach results in fewer complications at the puncture site, lower hospital costs, and greater comfort for patients.[ 1 , 7 ]

There are some reports of cardiac catheterizations and cerebral angiographies performed through a more distal radial approach, alternatively called the distal transradial approach (dTRA), snuffbox approach, or very dTRA.[ 2 , 8 , 11 ] Once the vessel is penetrated the technique is similar to the radial approach.

The dTRA approach has some benefits with respect to the conventional radial approach. These include (1) that arterial puncture is performed distal to the deep palmar arch formation, which ensures permeability of the palmar arch after the procedure; (2) that the neutral hand position is more comfortable for both the awake patient and the operator; and (3) that the left distal radial artery is more comfortable for the operator to puncture than the left traditional transradial approach. Another reason relates to the floor of the anatomical snuffbox being formed by two carpal bones – the trapezium and scaphoid – that being rigid structures, facilitate compression for hemostasis. Furthermore, subcutaneous hematomas rarely spread from the wrist to the upper part of the forearm, and there is no need to compress the wrist for hemostasis, which makes the wrist free to move and thereby limits venous congestion of the hand. Moreover, if vasospasm occurs or a hematoma develops from unsuccessful needling, thereby rendering further distal attempts more difficult, an operator can easily move proximal to adopt the conventional radial approach. Finally, the snuffbox approach saves more undamaged length of the radial artery for potential extracranial-intracranial artery bypass surgery candidates.[ 11 ]

There are some disadvantages of this approach: (a) the artery has a smaller caliber, more tortuous, and more vulnerable to spam in the anatomical snuffbox and needling can be more difficult than the conventional approach, due to the tortuosity a floppy 0.018 or 0.014-inch guide wire may be required; (b) needling theoretically can cause pain by irritating radial nerve and periosteum but there are no reports of this complication yet; (c) the scant soft tissue around the snuffbox might not secure the sheath properly; (d) since radial artery is smaller in caliber in the snuffbox, sheaths larger than 6Fr are difficult to be introduced; and (e) since there are many anatomic variations below the wrist across patients, the snuffbox approach is not always feasible.[ 8 ]

The objective of this paper is to describe the distal radial approach technique and the results obtained using it over the first 3 months during which this approach was employed for neuroendovascular diagnostic and therapeutic cerebral procedures at two centers at which the conventional radial approach had already been used as the first option for 3 years. The current cohort of patients is compared against those from the previous 3 months and to the frequency of needing to resort to a femoral approach.

MATERIALS AND METHODS

On March 25, 2019, puncture of the radial artery at the level of the anatomical snuffbox began to be used within two neurointerventional services as the first option for diagnostic or therapeutic cerebrovascular procedures involving patients over 18 years of age.

Description of the technique: for diagnostic procedures, local anesthesia is used at the puncture site, while general anesthesia is used for all therapeutic procedures. The distal radial approach is the first approach option currently employed, with failures progressing to the radial artery in the forearm within the pulse channel and then in cases of continued failure, the femoral approach.

For the distal radial approach, the boundaries of the anatomic snuffbox and radial artery path are demarcated [ Figure 1 ]. Aseptic techniques are utilized over the distal portion of the forearm and hand. The hand is placed on a sterile surface and covered with a sterile drape [ Figure 2 ]. The free forearm is supported on the sterile field and covered with a fenestrated plastic drape [ Figure 3 ]. If a left radial approach is needed, the same procedure is performed on the ipsilateral forearm, with the upper limb flexed and resting on the patient’s abdomen [ Figure 4 ]. Local infiltration is done with 2 cc of 1% Xylocaine. The radial artery is punctured between the tendon of the extensor pollicis longus and the tendons of the extensor pollicis brevis and abductor pollicis longus. A radial approach set (Merit Medical Systems, Utah, USA) is used, with a 6-French sheath placed using a modified Seldinger technique. Once the sheath is in position, 5 cc of nitroglycerin (200 µg/mL) are administered followed by 70 IU/kg of heparin [ Figure 5 ].


Figure 1:

The hand with the boundaries of the anatomic snuffbox and radial artery path demarcated in yellow lines.

 

Figure 2:

After aseptic technique preparation, the hand is covered with a sterile drape, and then the hand and forearm are placed on a sterile surface. The asterisk shows the position of the anatomical snuffbox while the dotted line the situation of the channel pulse.

 

Figure 3:

The free forearm supported on the sterile field and covered with a plastic fenestrated drape.

 

Figure 4:

The case in which bilateral approach was performed. Solid black arrow shows radial sheath inserted into the left radial artery through the snuffbox with the limb flexed and resting on the patient’s abdomen. Dotted arrow points out radial sheath inserted into the right radial artery through the classic transradial approach.

 

Figure 5:

Positioning of hand and anatomical landmarks for distal radial approach with the sheath located inside the radial artery. (a) Radial artery, (b) extensor pollicis longus tendon, (c) extensor pollicis brevis tendon, (d) abductor pollicis longus tendon, and (e) superficial palmar branch of the radial artery.

 

If the radial artery is not identified at the distal level, the hand is placed in supination and infiltration is performed approximately 2 cm above the wrist, where the radial pulse was marked in the pulse channel, according to a technique already described.[ 4 ] The procedure continues as described in previous articles on the diagnosis and treatment of cerebral aneurysms by the radial route.[ 3 , 4 ]

In programmed therapeutic cases, where it is not necessary to perform a 4-vessel diagnostic procedure, navigation is initially performed with a Chaperon guide catheter mounted on a Simmons catheter (MicroVention Inc., Tustin, CA, USA), while directly conducting catheterization of the carrier vessel with the guide catheter. In the remaining patients, in whom treatment is performed using the same procedure after diagnosis completed with a Simmons Type II catheter (Merit Medical Systems, Utah, USA), a 260 cm-long hydrophilic guide wire is passed through the external carotid artery and replacement made on the corresponding external carotid artery utilizing either one of two guide catheters: Guider Softip XF 6F (Stryker, Neurovascular Fremont, CA, USA), Navien (Medtronic Neurovascular, Irvine, CA, USA), or Sophia (MicroVention Inc., Tustin, CA, USA). Once in the vessel with pathology, the procedure continues as with any approach [ Figure 6 ].


Figure 6:

(a) Sheath penetrating radial artery through snuffbox, (b) guide catheter, (c) microcatheter, and (d) coil.

 

In one patient in whom there was a vertebrovertebral aneurysm, whereby vertebrobasilar flow diversion and occlusion of the contralateral artery had to be performed, both a right radial and left distal radial approach were used, with entrance of the guiding catheters into both vertebral arteries [ Figure 4 ]. Ultimately, this procedure was only diagnostic due to spontaneous thrombosis of the aneurysm. The maximum size of sheath used was 6Fr as in classic transradial approach described.[ 3 , 4 ]

Data analysis

Demographic and baseline clinical characteristics of the two patient cohorts – period 1 (last 3 months before distal radial approach use) and period 2 (first 3 months during which distal radial approach began to use) – were compared. Also were compared the rates at wich the femoral approach had to be used, overall and by gender.

RESULTS

Between March 25, 2019, and June 24, 2019 (period 2), a total of 94 endovascular procedures and 95 arterial punctures were performed (one procedure required a bilateral approach). Of these 94 procedures, 67 were diagnostic and 27 therapeutic; 27 (28%) were approached via femoral approach, 49 (51%) by radial route, and 19 (20%) by distal radial route. Of the 27 embolizations, 13 (48%) were performed through the radial approach, six (22%) through the femoral approach, and eight (30%) using the distal radial approach. Of the 68 punctures for angiography, 21 (30%) were performed through the femoral route, 36 (53%) by radial route, and 11 (16%) by distal radial route.

During period 1 (described previously), 80 procedures had been performed within the same two institutions: 65 diagnostic and 15 therapeutic, among which 38 had utilized the femoral route (47.5%) and 42 the radial route (52.5%). Of the 15 embolizations, two had been performed with radial approach and 13 through femoral approach. Of the angiographies, 40 (62%) and 25 (38%) had been done by radial and femoral route, respectively.

The mean age of patients in the first and second periods was 48 and 52 years old, respectively. The distribution by gender during the first period was 43 women and 37 men and in the second period 56 women and 38 men. In the first period, radial artery catheterization was used in 56% of the women, while in the second period when dTRA was added, the percentage of radial catheterization increased to 61% of the cases. In men, radial artery approach increased from 39% to 83%.

In this experience, using the dTRA as the first option for neuroendovascular procedures, 20% of the procedures were successful, with the full procedure completed through this approach. Of the therapeutic procedures (embolizations), 30% were successfully completed using the distal radial route, while success only was attained in 16% of the diagnostic procedures (cerebral angiographies).

When compared to a similar number of procedures performed over a similar period of time, we observed a reduction in the percentage of femoral approaches performed after adopting the dTRA as an option, from 47.5% to 28%. If only the embolizations are compared, we also observed a decline in the percentage of femoral approaches (from 87% to 22% of cases). If we compare the percentage of femoral approaches used for angiographies, the percentage fell from 38% to 30%. These data show an overall reduction in the rate of femoral approach use, both either for diagnostic or therapeutic purposes when the initial approach was distal radial. This trend did not change when men and women were analyzed separately.

Of the 27 embolizations performed within the second period, eight employed the distal radial approach, 13 the radial one, and only six the femoral route, meaning a significant decreased of femoral approaches.

The most obvious explanation for the observed decrease in femoral approaches between periods 1 and 2 is that when you start with a distal radial approach, you have a second option before resorting to the femoral route, which is not available if you begin with the classic radial approach. In this way, we can assume that at least some of the patients who ended up requiring a femoral procedure during the first period might have been spared that if the distal radial approach had been used initially.

CONCLUSION

Puncture of the radial artery within the anatomical snuffbox is another radial approach option for diagnostic and therapeutic neuroendovascular procedures and it appears to decrease the rate at which a femoral approach must ultimately be used.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

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