{"id":"78fb0846-f014-492f-9012-3bd0860aa6d4","slug":"a-rare-case-of-spinal-myeloid-sarcoma","title":"A rare case of spinal myeloid sarcoma","authors":["Wouter Deconinck","Sven Bamps","Thomas Steelandt","Maarten Wissels","Mark Plazier","Eric Put","Salah-Eddine Achahbar","Steven Vanvolsem","Sacha Meeuws","Sam Klein","Gert Roosen"],"abstract":"Background: Myeloid sarcoma (MS), a rare extramedullary tumor composed of myeloid blast cells, is classified by the World Health Organization as a subtype of acute myeloid leukemia (AML). Isolated, primary, or nonleukemic MS has an incidence of 2/1,000,000 adults and constitutes only 0.7% of all AML cases. MS presentations vary widely, with spinal involvement being rare. Case Description: A-year-old male presented with interscapular pain radiating to the right upper arm/neck but was neurologically intact. Once diagnosed with isolated spinal MS, he underwent a surgical decompression followed by local irradiation, systemic chemotherapy, and bone marrow transplantation. Eight months postoperatively, however, he experienced a graft-versus-host rejection and required additional therapies. Conclusion: Establishing the diagnosis of MS is challenging and typically requires histological confirmation (i.e., the presence of myeloblasts and granulocytic cells). However, optimal treatment strategies remain elusive; despite radiation, chemotherapy, bone marrow transplant/other local therapies, the overall long-term prognosis for MS remains poor.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/78fb0846-f014-492f-9012-3bd0860aa6d4/featured/hero-1781559071324.png","publishDate":"2024-11-15T00:00:00.000Z","doi":"10.25259/SNI_640_2024","categories":["Spine","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/api/articles/78fb0846-f014-492f-9012-3bd0860aa6d4/pdf"}