{"id":"64e8cc43-a781-4034-b6a8-c651f5ffc72c","slug":"a-rare-presentation-of-leiomyosarcoma-metastasis-to-the-cervical-spine-a-case-report-and-a-brief-review","title":"A rare presentation of leiomyosarcoma metastasis to the cervical spine: A case report and a brief review","authors":["Nenad Koruga","Alen Rončević","Anamarija Soldo Koruga","Jasmina Rajc","Josipa Flam","Tatjana Rotim","Tajana Turk","Sonja Škiljić","Marijan Cesarik","Tomislav Paun"],"abstract":"Background: Leiomyosarcoma (LMS) is a rare malignancy that originates from smooth muscle. The most common sites of metastases include the lungs, liver, kidney, and skin. Notably, metastases of LMS to the central nervous system/or spine are extremely rare. When a cervical spinal LMS lesion was encountered, the patient successfully underwent gross total tumor resection with negative margins. Case Description: A 63-year-old female had undergone an anterior cervical C5–C7 diskectomy and fusion 18 years ago and resection of a retroperitoneal LMS 3 years ago. She newly presented with right-sided numbness and pain of 2 months duration that correlated with a focal right-sided C5-level hemiparesis (i.e., 4/5 motor strength). When the cervical magnetic resonance demonstrated a right-sided C5 intralaminar mass with extension into the C5–C6 foramen, she underwent posterior tumor resection; pathologically, this proved to be an LMS metastasis. Respectively, 1- and six months postoperatively, follow-up magnetic resonance imaging scans showed no tumor recurrence; she tolerated adjuvant oncological treatment accompanied by physical therapy. However, in one postoperative year, the lesion recurred, and she is presently under consideration for additional surgical management. Conclusion: Gross total surgical resection is the first line of treatment for patients with metastatic LMS. Here, a patient with a C5 laminar/C5–C6 foraminal bony LMS metastasis underwent posterior tumor resection accompanied by adjuvant oncological treatment but exhibited disease recurrence within one postoperative year.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/64e8cc43-a781-4034-b6a8-c651f5ffc72c/featured/hero-1781559597134.png","publishDate":"2024-04-12T00:00:00.000Z","doi":"10.25259/SNI_66_2024","categories":["Spine","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/api/articles/64e8cc43-a781-4034-b6a8-c651f5ffc72c/pdf"}