{"id":"1d31b1b7-3f9a-48de-a399-3463e5364f01","slug":"adult-onset-giant-mediastinal-neuroblastoma","title":"Adult-onset giant mediastinal neuroblastoma","authors":["Ali Alkhaibary","Mohammed Abdulrazaq Alharbi","Sami Khairy"],"abstract":"Background: Neuroblastoma is a neurogenic tumor typically diagnosed in children <5 years of age. It arises from immature neural crest cells of the medulla of the adrenal gland or, less commonly, along the paravertebral sympathetic chain. We hereby report a patient with adult-onset giant mediastinal neuroblastoma. Case Description: A 34-year-old female presented with mid-thoracic back pain radiating to the ribs for 1 month. The neurological examination showed decreased sensation at the left T6–T12 dermatomes. Radiological imaging revealed a giant left mediastinal paravertebral soft-tissue lesion. The patient underwent a posterolateral thoracotomy and resection of the lesion. The histopathological sections were compatible with mediastinal neuroblastoma (Differentiating subtype). Conclusion: Adult-onset neuroblastoma has been rarely reported in the literature. The present article discusses the clinicoradiological features of an adult patient with giant mediastinal neuroblastoma.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/1d31b1b7-3f9a-48de-a399-3463e5364f01/featured/hero-1781558645472.png","publishDate":"2025-05-09T00:00:00.000Z","doi":"10.25259/SNI_800_2024","categories":["Neuro-oncology","Image Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2025/05/13549/SNI-16-170.pdf"}