{"id":"d52ea845-b365-4c22-8f21-b825a181bb7b","slug":"aggressively-recurring-cervical-intramedullary-anaplastic-astrocytoma-in-a-pregnant-patient","title":"Aggressively recurring cervical intramedullary anaplastic astrocytoma in a pregnant patient","authors":["James P. Caruso","Chen Shi","Benjamin Rail","Salah G. Aoun","Carlos A. Bagley"],"abstract":"Background: Many patients with spinal juvenile pilocytic astrocytoma can experience prolonged remission after resection. However, some reports suggest that pregnancy may be associated with progression. Case Description: The authors provide an image report highlighting a case of rapid and aggressive transformation of an intramedullary astrocytoma of the cervical spine in a pregnant patient. Over the course of 1 year, the lesion progressed from a juvenile pilocytic astrocytoma to an anaplastic astrocytoma. Genetic testing revealed mutations associated with aggressive behavior. Conclusion: The case and associated imaging demonstrate the importance of close neurologic monitoring and counseling regarding risk of progression in pregnant patients with spinal gliomas.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/d52ea845-b365-4c22-8f21-b825a181bb7b/featured/hero-1781562045490.png","publishDate":"2021-09-13T00:00:00.000Z","doi":"10.25259/SNI_759_2021","categories":["Spine","Image Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2021/09/11104/SNI-12-466.pdf"}