{"id":"b9bf90f7-8bef-4296-b54c-0c0ba2a555fc","slug":"aulogous-fibrin-sealant-vivostat-in-the-neurosurgical-practice-part-ii-vertebro-spinal-procedures","title":"Aulogous fibrin sealant (Vivostat<sup>®</sup>) in the neurosurgical practice: Part II: Vertebro-spinal procedures","authors":["Francesca Graziano","Rosario Maugeri","Luigi Basile","Favia Meccio","Domenico Gerardo Iacopino"],"abstract":"Background: Epidural hematomas, cerebrospinal fluid fistula, and spinal infections are challenging postoperative complications following vertebro-spinal procedures. We report our preliminary results using autologous fibrin sealant as both fibrin glue and a hemostatic during these operations. Methods: Prospectively, between January 2013 and March 2015, 68 patients received an autologous fibrin sealant prepared with the Vivostat® system applied epidurally to provide hemostasis and to seal the dura. The surgical technique, time to bleeding control, and associated complications were recorded. Results: Spinal procedures were performed in 68 patients utilizing autologous fibrin glue/Vivostat® to provide rapid hemostasis and/or to seal the dura. Only 2 patients developed postoperative dural fistulas while none exhibited hemorrhages, allergic reactions, systemic complications, or infections. Conclusions: In this preliminary study, the application of autologous fibrin sealant with Vivostat® resulted in rapid hemostasis and/or acted as an effective dural sealant. Although this product appears to be safe and effective, further investigations are warranted.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/b9bf90f7-8bef-4296-b54c-0c0ba2a555fc/featured/hero-1782420951379.png","publishDate":"2016-01-25T00:00:00.000Z","doi":"10.4103/2152-7806.174894","categories":["Spine","Original Article"],"fullTextUrl":"http://surgicalneurologyint.com/wp-content/uploads/2016/02/6447/SNI-7-77.pdf"}