{"id":"ef62f7d8-57f3-42c1-be20-5945e510933c","slug":"brain-metastasis-from-a-thoracic-myxofibrosarcoma-a-case-report-and-literature-review","title":"Brain metastasis from a thoracic myxofibrosarcoma: A case report and literature review","authors":["Otávio da Cunha Ferreira Neto","Roberto Borges Bezerra","Rhuann Pontes dos Santos Silva","Melissa Helena Rodrigues Silva","Joaquim Fechine de Alencar Neto","Arthur José Maia Lopes"],"abstract":"Background: Myxofibrosarcoma (MFS) is a type of sarcoma that mainly affects elderly people; it represents only 5% of all sarcomas and shows no line of differentiation. Intracranial MFS is a rare condition. At present, limited data exist regarding brain metastasis from MFS. This article reports a case of MFS and reviews the literature regarding MFS metastasis. Case Description: We report a case of brain metastasis from chest wall MFS. The patient was diagnosed with an anterior thoracic MFS and underwent surgery and radiotherapy. One year later, he noticed a tumor on his left shoulder, and more than 1 year thereafter, bilateral lung metastasis was observed. Twelve months after lung metastasis, he presented to the emergency department and underwent contrast-enhanced magnetic resonance imaging, which demonstrated a left frontal tumor suggestive of brain metastasis. Since the main hypothesis was a sarcoma metastasis at the location close to the left motor area, and the patient had a good Karnofsky performance scale, the patient underwent neuronavigation-guided surgery. After surgery, the patient developed Grade III hemiparesis and aphasia. Brain tumor histopathology confirmed a malignant neoplasm with osteosarcomatous differentiation and metastasis from MFS. Conclusion: We report a rare case of MFS metastasis. To the best of our knowledge, this is the eighth case of intracerebral metastasis from MFS.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/ef62f7d8-57f3-42c1-be20-5945e510933c/featured/hero-1781560726141.png","publishDate":"2022-11-18T00:00:00.000Z","doi":"10.25259/SNI_717_2022","categories":["Neuro-oncology","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/api/articles/ef62f7d8-57f3-42c1-be20-5945e510933c/pdf"}