{"id":"d5ed4134-1435-4068-bcea-836df7199b50","slug":"cerebrospinal-fluid-protein-concentration-in-patients-with-lumbar-spinal-stenosis","title":"Cerebrospinal fluid protein concentration in patients with lumbar spinal stenosis","authors":["Hitoshi Yamahata","Kosei Ijiri","Fumito Tanabe","Kyoichi Murasumi","Yushi Nagano","Ryutaro Makino","Nayuta Higa","Ryosuke Hanaya"],"abstract":"Background: In this study, we examined the impact and degree of lumbar stenosis on cerebrospinal fluid (CSF) protein concentration. Methods: In this retrospective study, we analyzed protein concentrations in CSF samples of 61 patients with lumbar spinal stenosis (LSS) obtained during pre-operative myelography. Patients were divided into two groups: those showing no block to contrast (Group A) versus those showing medium block to contrast below the lumbar puncture level (Group B). Results: The CSF protein concentration in Group B (104.3 ± 59 g/dL) patients with medium block was significantly greater than that in Group A (65.1 ± 33 g/dL) patients without medium block. Conclusion: A higher average CSF protein concentration was seen in Group B patients with significant lumbar stenosis versus Group A patients without significant lumbar stenosis. Theoretically, damage to the cauda equina in patients with LSS may cause these elevated CSF protein levels.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/d5ed4134-1435-4068-bcea-836df7199b50/featured/hero-1781559310163.png","publishDate":"2024-08-23T00:00:00.000Z","doi":"10.25259/SNI_610_2024","categories":["Spine","Original Article"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2024/08/13051/SNI-15-303.pdf"}