{"id":"60ed3f1b-810c-4d35-89fc-7e2423bd2416","slug":"cervicomedullary-glioblastoma-a-report-of-two-cases-with-review-of-literature","title":"Cervicomedullary glioblastoma: A report of two cases with review of literature","authors":["Chandan Mohanty","Kalp Shandilya","Chandrasekhar Eknath Deopujari","Gaurav Gupta","Vikram Karmarkar","Sunila Jaggi"],"abstract":"Background: Cervicomedullary glioblastoma is an extremely rare clinical entity and the principles of its management are not well understood. Case Description: We report two cases of cervicomedullary glioblastoma in young patients aged 12 and 30 years with contrasting clinical presentation and outcomes. The 12-year-old child had rapid onset bulbar symptoms, with frank infiltration of the medulla due to which the patient succumbed within 4 weeks of surgery. The 30-year-old adult had a relatively slow disease onset and progression and made a good neurological recovery without disease progression at 16 months after surgery. To the best of our knowledge, we also report only the second adult patient in the literature with a dorsally exophytic cervicomedullary glioblastoma. Difficulties in diagnosis and management are discussed with a review of the pertinent literature. Conclusion: The overall outcome depends on the rapid progression and severity of preoperative symptoms and the degree of tumor infiltration noted in imaging and during surgery.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/60ed3f1b-810c-4d35-89fc-7e2423bd2416/featured/hero-1781560646567.png","publishDate":"2022-12-16T00:00:00.000Z","doi":"10.25259/SNI_581_2022","categories":["Neuro-oncology","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2022/12/12062/SNI-13-579.pdf"}