{"id":"b9c74fdd-bf1a-40cb-9a5d-f242a0f77574","slug":"collision-tumor-comprised-of-chronic-lymphocytic-leukemia-and-myxopapillary-ependymoma","title":"Collision tumor comprised of chronic lymphocytic leukemia and myxopapillary ependymoma","authors":["Ahmed Aly","Santhosh Nagaraju","Rupert Price"],"abstract":"Background: Collision tumors involving the co-occurrence of two morphologically and genomically distinct neoplasms in the same anatomical site are exceptionally rare in the central nervous system (CNS). Case Description: We report a unique case of a CNS collision tumor comprising chronic lymphocytic leukemia and myxopapillary ependymoma in a 77-year-old male with acute neurological decline. Presumed to represent leukemic infiltration, urgent laminectomy was pursued for tissue diagnosis and spinal cord decompression, revealing the unexpected ependymal component. Conclusion: This case highlights the diagnostic and therapeutic challenges inherent to managing collision CNS tumors, particularly when one neoplasm is hematological.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/b9c74fdd-bf1a-40cb-9a5d-f242a0f77574/featured/hero-1781559340131.png","publishDate":"2024-08-09T00:00:00.000Z","doi":"10.25259/SNI_658_2023","categories":["Neuro-oncology","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2024/08/13028/SNI-15-282.pdf"}