{"id":"162bb7ce-f448-443b-84e4-6af5b064e7f0","slug":"combined-microscopic-transoral-and-endoscopic-endonasal-approach-for-a-clival-chordoma-a-case-report-and-literature-review","title":"Combined microscopic transoral and endoscopic endonasal approach for a clival chordoma: A case report and literature review","authors":["Marco Antonio Munuzuri-Camacho","Ricardo Palacios-Rodriguez","Jorge Alanis-Mendizabal","Tomas Moncada-Habib","Marcos V. Sangrador-Deitos","Obet Jair Canela-Calderon","Victor Alcocer-Barradas"],"abstract":"Background: Chordomas are primary bone tumors derived from the embryonic notochord. They represent 1–4% of all malignant bone tumors. They have a predominantly extra-axial location, arising in the clival region in 35% of reported cases. The prognosis is generally poor, and radical resection remains the first-line treatment. This study aims to describe a case of a clival chordoma that was resected through a combined microscopic transoral and endoscopic endonasal approach, with excellent clinical outcomes. Case Description: A 24-year-old woman with low cranial nerve symptomatology was admitted for a two-stage surgical approach. An occipital-cervical fixation was performed in the first stage, while a combined endonasaltransoral resection was performed later for tumor resection. Conclusion: Microscopic transoral and endoscopic endonasal approaches offer advantages for treating clival chordomas, with careful consideration of anatomical constraints and potential for postoperative recurrence being essential in approach selection.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/162bb7ce-f448-443b-84e4-6af5b064e7f0/featured/hero-1781559128533.png","publishDate":"2024-10-25T00:00:00.000Z","doi":"10.25259/SNI_323_2024","categories":["Skull Base","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2024/10/13169/SNI-15-383.pdf"}