{"id":"12394760-a034-4fe0-b4db-5ac10f9d2ed2","slug":"convexity-meningiomas-enhanced-by-sodium-fluorescein","title":"Convexity meningiomas enhanced by sodium fluorescein","authors":["Carlos Eduardo da Silva","Vinicius Duval da Silva","Jefferson Luis Braga da Silva"],"abstract":"Background: The resection of the meningiomas surrounding the dura is an important goal during the removal of a convexity meningioma. The authors present the first application of sodium fluorescein (SF) as a tool for tumor and dural tail identification in convexity meningiomas. Methods: Five frontal convexity meningiomas operated on between December 2012 and April 2013 were included. After initial dissection a dose of 1 g of the SF, 20% was injected into a peripheral vein. Tumor and dural tail were removed using the correlation between magnetic resonance imaging (MRI) findings and transoperative SF enhancement. Results: Simpson Grade 1 removal was obtained in three cases, grade 2 in one atypical meningioma and grade zero in one case. SF dural tail enhancement was positive in all cases and histologic analysis evidenced involvement of the dura by tumors. Conclusion: SF enhancement was evident in meningiomas and dura surrounding the lesions. Histologic analysis confirmed dural involvement. SF could represent an universally available fluorescent tool for meningioma surgery.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/12394760-a034-4fe0-b4db-5ac10f9d2ed2/featured/hero-1782420831343.png","publishDate":"2014-01-14T00:00:00.000Z","doi":"10.4103/2152-7806.124978","categories":["Original Article"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2015/05/3599/SNI-5-3.pdf"}