{"id":"d21cf724-708e-4760-b9da-eb9a359fc91d","slug":"current-advancements-in-the-management-of-spinal-cord-injury-a-comprehensive-review-of-literature","title":"Current advancements in the management of spinal cord injury: A comprehensive review of literature","authors":["Manan Shah","Catherine Peterson","Emre Yilmaz","Dia Radi Halalmeh","Marc Moisi"],"abstract":"Background: Spinal cord injury (SCI) carries debilitating lifelong consequences and, therefore, requires careful review of different treatment strategies. Methods: An extensive review of the English literature (PubMed 1990 and 2019) was performed regarding recent advances in the treatment of SCI; this included 46 articles written over 28 years. Results: Results of this search were divided into five major modalities; neuroprotective and neuroregenerative pharmaceuticals, neuromodulation, stem cell-based therapies, and various external prosthetic devices. Lately, therapeutic strategies were mainly focused on two major areas: neuroregeneration and neuroprotection. Conclusion: Despite recent advancements, more clinical trials on a larger scale and further research are needed to provide better treatment modalities of this devastating neurological disease.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/d21cf724-708e-4760-b9da-eb9a359fc91d/featured/hero-1781563643617.png","publishDate":"2020-01-03T00:00:00.000Z","doi":"10.25259/SNI_568_2019","categories":["Spine","Review Article"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2020/01/9833/SNI-11-2.pdf"}