{"id":"b59413ee-e814-44a4-b4b4-04e1221a9974","slug":"demographic-and-regional-patterns-of-epilepsy-related-mortality-in-the-usa-insights-from-cdc-wonder-data","title":"Demographic and regional patterns of epilepsy-related mortality in the USA: Insights from CDC WONDER data","authors":["Javed Iqbal","Muhammad Ashir Shafique","Burhanuddin Sohail Rangwala","Hafsah Alim Ur Rahman","Muhammad Abdullah Naveed","Afia Fatima","Ahila Ali","Tirath Patel","Moosa Abdur Raqib","Muhammad Saqlain Mustafa","Abdul Haseeb","Sandesh Raja","Adarsh Raja","Stephanie Hage","Mohammad Ashraf"],"abstract":"Background: Epilepsy poses significant challenges globally, with varied clinical, social, and economic impacts. Despite advances in treatment, epilepsy-related mortality remains a concern. This study aimed to analyze the demographic and regional distributions of epilepsy-related mortality in the United States (U.S.) from 1999 to 2020, identifying high-risk populations for targeted interventions. Methods: Data on death certificates were obtained from the 1999 to 2020 Centers for Disease Control and Prevention Wide-Ranging Online Study Epidemiologic Research (CDC-WONDER) database. We gathered data on demographics, place of death, and urban/rural classification. Mortality rates per 100,000 people were computed and classified according to state, year, sex, race/ethnicity, and urban/rural status. Trends were examined using Joinpoint regression. Results: A total of 12,573 deaths (age less than 35), 22,947 (35–64), and 21,782 (65+) were attributed to epilepsy. Mortality rates varied by age group, sex, race/ethnicity, and region. Trends showed significant increases, notably in middle-aged and older adults, with higher rates in males and nonHispani, African American populations. Conclusion: Epilepsy-related mortality exhibits demographic and regional disparities in the U.S. Understanding these patterns can guide targeted interventions to mitigate mortality risk.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/b59413ee-e814-44a4-b4b4-04e1221a9974/featured/hero-1781559016581.png","publishDate":"2024-12-06T00:00:00.000Z","doi":"10.25259/SNI_592_2024","categories":["Epilepsy","Review Article"],"fullTextUrl":"https://surgicalneurologyint.com/api/articles/b59413ee-e814-44a4-b4b4-04e1221a9974/pdf"}