{"id":"37d495ad-0e5e-44fc-bfae-2c6e92f246c4","slug":"diffuse-large-b-cell-lymphoma-in-the-sphenoid-sinus-a-case-report-and-review-of-literature","title":"Diffuse large B-cell lymphoma in the sphenoid sinus: A case report and review of literature","authors":["Daisuke Wajima","Fumihiko Nishimura","Katsuya Masui"],"abstract":"Background: Non-Hodgkin lymphomas (NHLs) in paranasal sinus are uncommon, accounting for 0.17–2% of all NHL cases; it is especially rare in the sphenoid sinus. In this report, we describe a case of NHL in the sphenoid sinus. Case Description: A 66-year-old man presented with a sudden left eye movement disorder. His head computed tomography and gadolinium-enhanced magnetic resonance imaging (Gd-MRI) showed a mass lesion extending around the left sphenoid sinus. However, the tumor regrowth about twice was observed during 2 weeks, partial removal of tumor was performed by the endoscopic trans-nasal transsphenoidal surgery, then histologically proved it to be diffuse large B-cell lymphoma (DLBCL). After R-THP-COP regimen (rituximab 375 mg/m2, Conclusion: NHLs in the sphenoid sinus is very rare disease, however, it is important to be diagnosed pathologically as soon as possible for being in remission state by the chemotherapy.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/37d495ad-0e5e-44fc-bfae-2c6e92f246c4/featured/hero-1781563294489.png","publishDate":"2020-07-25T00:00:00.000Z","doi":"10.25259/SNI_280_2020","categories":["Neuro-oncology","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2020/07/10155/SNI-11-208.pdf"}