{"id":"b86f694a-99f1-4482-aebd-f3a8285c9259","slug":"fetal-subependymal-giant-cell-astrocytoma-a-case-report-and-review-of-the-literature","title":"Fetal subependymal giant cell astrocytoma: A case report and review of the literature","authors":["Aikaterini Karagianni","Ploutarchos Karydakis","Dimitrios Giakoumettis","Ioannis Nikas","George Sfakianos","Marios Themistocleous"],"abstract":"Background: Subependymal giant cell astrocytomas (SEGAs) appear approximately in 10% of patients with tuberous sclerosis. These tumors are most commonly diagnosed in childhood and adolescence, with in utero diagnosed SEGAs being an extremely rare entity. Case Description: We present the case of a congenital SEGA detected in an antenatal ultrasound and further investigated with fetal magnetic resonance imaging (MRI) scans at 22 and 32 weeks of gestational age. At 9 days of age, the child underwent craniotomy and partial excision of the tumor, followed by a second more extensive operation 13 days later. The patient was subsequently administered mammalian target of rapamycin inhibitor (everolimus). Conclusion: In the latest follow-up MRI, at the age of two, the SEGA remained unchanged. Management of these tumors in neonates is challenging, mainly due to high morbidity and mortality of surgical treatment in these ages.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/b86f694a-99f1-4482-aebd-f3a8285c9259/featured/hero-1781563596482.png","publishDate":"2020-02-25T00:00:00.000Z","doi":"10.25259/SNI_10_2019","categories":["Pediatric Neurosurgery","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2020/02/9878/SNI-11-26.pdf"}