{"id":"681fca45-f4be-437b-b2cc-2df39c5ab3ed","slug":"glioma-mimicking-a-cystic-infectious-disease-a-case-report-of-multifocal-multicentric-cystic-glioblastoma","title":"Glioma mimicking a cystic infectious disease: A case report of multifocal, multicentric cystic glioblastoma","authors":["Daniel Kiss-Bodolay","Marc Weiner","Kristof Egervari","Gilles Eperon","Maria Isabel Vargas","Denis Migliorini","Johannes Lobrinus","Stephan Harbarth","Philippe Bijlenga"],"abstract":"Background: Glioblastoma multiforme (GBM) is a highly aggressive malignant tumor known to be a great mimicker. Multicystic metastasis and cystic GBM are not rare but multicystic diffuse GBM was never reported before. Case Description: We describe here the clinical course, the radiological characteristics, and the management of a patient with a diffuse cystic brain lesion. Even though the comprehensive bacterial, fungal, and parasitic work-up came back negative twice, the radiological and biological findings of the case presented in this work mislead an experienced multidisciplinary team. In a somewhat unexpected way, the pathological results showed a high-grade glial tumor. Conclusion: The case reported herein is an important reminder of the highly multimorph characteristics of GBM and the challenging differential diagnosis of cystic brain lesions.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/681fca45-f4be-437b-b2cc-2df39c5ab3ed/featured/hero-1781558505252.png","publishDate":"2025-06-20T00:00:00.000Z","doi":"10.25259/SNI_56_2025","categories":["Neuro-oncology","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2025/06/13654/SNI-16-248.pdf"}