{"id":"e69a5960-9a84-409c-8a17-dc71c658d37d","slug":"gorham-stout-disease-of-the-spine-presenting-with-intracranial-hypotension-and-cerebrospinal-fluid-leak-a-case-report-and-review-of-the-literature","title":"Gorham-Stout disease of the spine presenting with intracranial hypotension and cerebrospinal fluid leak: A case report and review of the literature","authors":["Hana Yokoi","Vikram Chakravarthy","Benjamin Whiting","Scott E. Kilpatrick","Tsulee Chen","Ajit Krishnaney"],"abstract":"Background: Gorham-Stout (GS) disease or “vanishing bone disease” is rare and characterized by progressive, spontaneous osteolysis resulting in loss of bone on imaging studies. Treatment modalities include combinations of medical and/or surgical treatment and radiation therapy. Case Description: A 14-year-old female with GS disease presented with a 1-year history of thoracic back pain and atypical headaches consistent with intracranial hypotension. Magnetic resonance imaging and operative findings demonstrated a spontaneous thoracic cerebrospinal fluid leak (CSF) (e.g., that extended into the pleural cavity) and complete osteolysis of the T9-10 posterior bony elements (e.g., including the rib head, lamina, and transverse processes). The patient underwent repair of CSF fistula followed by a T6-11 instrumented fusion. Conclusion: This case of GS disease, involving a thoracic CSF fistula and absence/osteolysis of the T9-T10 bony elements, could be successfully managed with direct dural repair and an instrumented T6-T11 fusion.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/e69a5960-9a84-409c-8a17-dc71c658d37d/featured/hero-1781562822664.png","publishDate":"2020-12-29T00:00:00.000Z","doi":"10.25259/SNI_618_2020","categories":["General Neurosurgery","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2020/12/10502/SNI-11-466.pdf"}