{"id":"2bb873d2-dd7d-49be-9500-3a6781e50e32","slug":"immunoglobulin-g4-related-disease-presenting-as-an-intracranial-mass-extended-from-the-infratemporal-fossa","title":"Immunoglobulin G4-related disease presenting as an intracranial mass extended from the infratemporal fossa","authors":["Kais Maamri","Mohamed Amine Hadj Taieb","Ghassen Elkahla","Rym Hadhri","Mehdi Dermoul"],"abstract":"Background: Neurological manifestations in immunoglobulin G4-related diseases (IgG4-RD) are rare and documented in <2% of cases. It commonly involves pachymeninges forming hypertrophic pachymeningitis and rarely forms tumor-like masses. Case Description: We present our experience with a biopsy-proven case of IgG4-RD presenting with an intracranial extradural tumor-like mass infiltrating the temporal lobe. The patient was treated with high doses of corticosteroids followed by slow tapering. The neurological manifestations gradually improved and resolved after 2 months with a cerebral MRI showing a significant reduction in the tumoral size. Conclusion: When it comes to intracranial mass, IgG4-RD neuropathy is one of the rarest differential diagnoses for the central nervous system tumors. Early recognition of IgG4-RD and appropriate establishment of its long-term treatment may avoid unnecessary investigations and morbidity.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/2bb873d2-dd7d-49be-9500-3a6781e50e32/featured/hero-1781561320718.png","publishDate":"2022-05-27T00:00:00.000Z","doi":"10.25259/SNI_149_2022","categories":["Neuro-oncology","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2022/05/11619/SNI-13-224.pdf"}