{"id":"87148bec-9a7c-4582-ac69-9c1ac9e3b739","slug":"intracranial-extramedullary-hematopoiesis-in-a-patient-with-beta-thalassemia-presenting-with-head-trauma","title":"Intracranial extramedullary hematopoiesis in a patient with beta-thalassemia presenting with head trauma","authors":["Noah M. Nichols","Ashia M. Hackett","Alejandro Carrasquilla","Paul Solodnik","Hang Byun","Salazar Jones","Zachary L. Hickman"],"abstract":"Background: Beta-thalassemia is an inherited hemoglobinopathy, whereby reduced or absent expression of beta-globin genes causes impaired erythropoiesis. Extramedullary hematopoiesis (EMH) occurs in 1% of all patients with beta-thalassemia major receiving regular transfusions and is exceedingly rare intracranially. Case Description: We report a case of a male in his 20s with beta thalassemia who presented with head trauma found to have intracranial EMH mimicking multiple extra-axial hematomas. Making the correct diagnosis was critical in avoiding prolonged neuromonitoring and unnecessary interventions. Conclusion: Intracranial extramedullary hematopoietic pseudotumor is an exceedingly rare entity and seldom appears in a neurosurgeon’s differential diagnosis. This case illustrates how this condition can easily mimic an acute intracranial hemorrhage in a patient with beta-thalassemia who presents with head trauma. We review the topic to further inform clinicians who may encounter this condition in their practice.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/87148bec-9a7c-4582-ac69-9c1ac9e3b739/featured/hero-1781560734976.png","publishDate":"2022-11-18T00:00:00.000Z","doi":"10.25259/SNI_730_2022","categories":["Trauma","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/api/articles/87148bec-9a7c-4582-ac69-9c1ac9e3b739/pdf"}