{"id":"3bb3b7bc-c94d-4916-ad80-d2f533d22abd","slug":"intradural-extramedullary-eosinophilic-granuloma-of-the-spine-with-emergency-presentation-a-case-report","title":"Intradural extramedullary eosinophilic granuloma of the spine with emergency presentation: A case report","authors":["Wamedh Esam Matti","Hussain J. Kadhum","Ibtisam Hussein Al Obaidi","Maher Khashea Mustafa","Ahmed Maan Taha Mustafa","Rasha Alaa Alshakarchy","Mustafa Ismail"],"abstract":"Background: Intradural extramedullary spinal eosinophilic granuloma is a very unusual manifestation of Langerhans Cell Histiocytosis (LCH) that is typically misdiagnosed due to its nonspecific clinical and radiological features. Case Description: We report a case of a 22-year-old female patient who presented with acute onset paraplegia. The magnetic resonance imaging was initially suggestive of tuberculoma, which is prevalent in tuberculosis-endemic regions. Intraoperative findings and histopathology, however, established the diagnosis of LCH. The lesion was intradural, and CD1a and S-100 protein staining demonstrated classic Langerhans cells. Conclusion: The paper stresses the need for a multidisciplinary team in the proper diagnosis and handling of spinal LCH. Further research is needed to develop optimal management protocols for this rare condition.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/3bb3b7bc-c94d-4916-ad80-d2f533d22abd/featured/hero-1781558788785.png","publishDate":"2025-03-21T00:00:00.000Z","doi":"10.25259/SNI_581_2024","categories":["Unique Case Observations","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2025/03/13451/SNI-16-94.pdf"}