{"id":"5e766671-f0ee-4836-a982-27e61cf9a825","slug":"l5-giant-cell-tumor-in-28-year-old-female","title":"L5 giant cell tumor in 28-year-old female","authors":["Wisnu Baskoro","Muhammad Fakhri Raiyan Pratama","Early Isnaeni Nur Fauziah","Hanan Anwar Rusidi","Bidari Kameswari"],"abstract":"Background: Giant cell tumor of bone (GCTB) is a rare benign tumor that may also exhibit aggressive local behavior. Recurrence of GCTB is common even after complete resection. GCTB typically occurs in long bones, and only 2.7% are found in the spine. Here, a 28-year-old female with a magnetic resonance (MR)-documented L5 lumbar spine GCTB presented with a cauda equina syndrome effectively managed with a decompressive laminectomy/L4–S1 fusion. Case Description: A 28-year-old female presented with a 1-year history of lower extremity pain/paresthesia that had exacerbated over the previous 1 month. When the MR imaging revealed cauda equina compression due to a L5 hypodense lesion, the patient successfully underwent a decompressive laminectomy/L4–S1 fusion. The histopathology examination confirmed the presence of a GCTB. Conclusion: While gross total excision for GCTB is the treatment of choice, for those undergoing only subtotal/partial resections, additional adjuvant therapy may be warranted. Notably, even despite extensive resections, these lesions have a high rate of recurrence.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/5e766671-f0ee-4836-a982-27e61cf9a825/featured/hero-1781559025505.png","publishDate":"2024-11-29T00:00:00.000Z","doi":"10.25259/SNI_533_2024","categories":["Neuro-oncology","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2024/11/13262/SNI-15-436.pdf"}