{"id":"c5920d02-edfc-45f6-a6af-5210df4b8c0a","slug":"letter-to-editor-regarding-neurosurgical-emergencies-during-pregnancy-management-dilemmas","title":"Letter to editor regarding “Neurosurgical emergencies during pregnancy-management dilemmas”","authors":["Ajay Nair","Andrew Waack","Soumya Sharma","Alastair Hoyt","Jason Schroeder"],"abstract":"Background: Glioblastoma multiforme (GBM) during pregnancy presents significant challenges in neurosurgical management for both the expectant mother and fetus. The Stupp protocol, which includes surgical resection, requires careful consideration of intraoperative factors that could affect fetal health, such as blood loss and anesthesia-induced hypotension. Summary: The authors discuss the complexities of managing GBM during pregnancy, emphasizing the importance of timing surgical interventions, with the second trimester being preferred. They highlight the risks associated with chemotherapeutic agents like temozolomide and radiation therapy, which can have detrimental effects on fetal development and maternal health. Conclusion: Treating GBM during pregnancy is a formidable challenge that necessitates a cautious approach, taking into account the unique risks to both the mother and fetus. A comprehensive evaluation of maternal and fetal conditions is essential for optimizing treatment outcomes. Keywords: glioblastoma, pregnancy, neurosurgery, temozolomide, radiation therapy, surgical management, fetal health","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/placeholders/specialty/neuro-oncology.png","publishDate":"2023-12-08T00:00:00.000Z","doi":"10.25259/SNI_729_2023","categories":["Neuro-oncology","Letter to the Editor"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2023/12/12659/SNI-14-421.pdf"}