{"id":"442eba5c-fbee-44e5-9871-dcf79653c74b","slug":"letter-to-the-editor-transneural-transmission-in-covid-19-without-a-positive-nasopharyngeal-swab","title":"Letter to the Editor: Transneural transmission in COVID-19 without a positive nasopharyngeal swab","authors":["Ahmed Ansari","Sadaf Riyaz"],"abstract":"Background: The article discusses the implications of COVID-19 in neurosurgery, emphasizing the need for treating all patients as potential positive cases. It highlights instances where cerebrospinal fluid (CSF) tested positive for COVID-19 despite negative nasopharyngeal swabs, raising concerns about brain infections in COVID-19 patients. Summary: The authors propose that SARS-CoV-2 may invade the brain through olfactory pathways, particularly affecting areas like the medial temporal cortex and hippocampus. They suggest that some COVID-19 patients may present with minimal respiratory symptoms while experiencing significant neurological manifestations, necessitating a heightened awareness among healthcare providers. Conclusion: The letter underscores the importance of recognizing the potential for transneural transmission of COVID-19 and the need for vigilance in diagnosing and managing neurological complications in patients during the pandemic. Keywords: COVID-19, neurosurgery, transneural transmission, olfactory pathway, brain infection, cerebrospinal fluid, neurological complications","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/placeholders/specialty/general-neurosurgery.png","publishDate":"2020-09-12T00:00:00.000Z","doi":"10.25259/SNI_335_2020","categories":["General Neurosurgery","Letter to the Editor"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2020/09/10256/SNI-11-284.pdf"}