{"id":"ab1464d7-7a37-47a4-88ea-8d36f0db3387","slug":"lumbar-intradural-extramedullary-plexiform-schwannoma-a-case-report-and-literature-review","title":"Lumbar intradural extramedullary plexiform schwannoma: A case report and literature review","authors":["Ana Brito-Seixas","Joana Martins","Pedro De Vasconcelos","Sérgio Livraghi","Martin Lorenzetti"],"abstract":"Background: Plexiform schwannomas are rare lesions with different histopathological variants (i.e., multifocal, intraneural, and multinodular). They comprise ~5% of schwannomas and rarely occur in the spinal canal. Here, a 40-year-old male presented with an exceedingly rare plexiform schwannoma. Case Description: A 40-year-old male presented with low back pain, bilateral L3 radiculopathy, and mild L3-level hypoesthesias. The pre-operative lumbar magnetic resonance imaging (MRI) showed an intradural extramedullary, multinodular L3 mass, isointense on T1-weighted imaging, homogeneously hyperintense on T2-weighted imaging, and markedly enhancing with contrast. Gross total microsurgical resection was achieved through an L3 laminectomy. The histopathology revealed a plexiform schwannoma (World Health Organization Grade 1). The post-operative MRI confirmed complete tumor removal, and six months later, the patient remained asymptomatic. Conclusion: Microsurgical gross total resection is the mainstay treatment for rare symptomatic lumbar plexiform schwannomas.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/ab1464d7-7a37-47a4-88ea-8d36f0db3387/featured/hero-1781558091654.png","publishDate":"2025-12-19T00:00:00.000Z","doi":"10.25259/SNI_1162_2025","categories":["Spine","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2025/12/14165/SNI-16-537.pdf"}