{"id":"29f04650-35c1-4373-a1a2-35367447c5b4","slug":"malignant-glioma-primitive-neuroectodermal-tumor-recurring-as-pnet-like-only-subdural-collection-case-report","title":"Malignant glioma-primitive neuroectodermal tumor recurring as PNET-like only subdural collection: Case report","authors":["Anthony M. Alvarado","Michael E. Salacz","Roukoz B. Chamoun"],"abstract":"Background: Histologic variants of conventional glioblastoma are rare clinical entities. In recent years, an aggressive variant termed malignant glioma with primitive neuroectodermal tumor components (MG-PNET) has been described in adults. In addition to the rarity of supratentorial primitive neuroectdoermal tumors (sPNET) in adults, MG-PNET can present with unique radiographic features. Case Description: We report the case of a 42-year-old male who presented with headaches and vision changes. Magnetic resonance imaging (MRI) of the brain revealed a large right frontal lesion. He underwent craniotomy with pathology demonstrating glioblastoma WHO grade IV, with primitive neuroectodermal tumor-like components (MG-PNET). Seven weeks later the patient represented with worsening headaches and left-hand weakness. MRI brain revealed a diffusion restricting subdural collection overlying the prior craniotomy site. Biopsy revealed PNET-like recurrence of the previously treated MG-PNET. Conclusion: In addition to histologic deviation, MG-PNET can present with variable radiographic findings on MRI and a clinical course distinctive from traditional glioblastoma. The hypercellular nature of this lesion can present as a diffusion-restricting lesion.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/29f04650-35c1-4373-a1a2-35367447c5b4/featured/hero-1782420894465.png","publishDate":"2017-10-10T00:00:00.000Z","doi":"10.4103/sni.sni_24_17","categories":["Neuro-oncology","Case Report"],"fullTextUrl":"http://surgicalneurologyint.com/wp-content/uploads/2017/10/8631/SNI-8-243.pdf"}