{"id":"270624db-1b75-47e4-8c73-e698126c94b1","slug":"malignant-peripheral-nerve-sheath-tumor-of-the-scalp-two-rare-case-reports","title":"Malignant peripheral nerve sheath tumor of the scalp: Two rare case reports","authors":["Muhammad Firdaus","Arwinder Singh Gill","Dewi Aisiyah Mukarramah","Rini Andriani","Lenny Sari","Dian Cahyanti","Ahmad Faried"],"abstract":"Background: Malignant peripheral nerve sheath tumors (MPNSTs) constitute a group of soft tissue neoplasm with neuroectodermal origin. Most cases are small at presentation and only some have been described reaching giant dimensions. Case Description: We report two cases that were diagnosed and treated as giant MPNST of the scalp. Both patients had extensive lesion on the head with intracranial infiltration. Microsurgical resection was indicated and a vascularized free flap was used to cover the defect. During follow-up the tumors recurred and further surgical excision treatment by adjuvant radiation therapy was performed. Conclusion: MPNSTs of the scalp are rare neoplasm of the peripheral nervous system. They are aggressive lesion that can recur and their management requires a multimodality approach.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/270624db-1b75-47e4-8c73-e698126c94b1/featured/hero-1782420860219.png","publishDate":"2018-05-15T00:00:00.000Z","doi":"10.4103/sni.sni_196_17","categories":["Neuro-oncology","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/api/articles/270624db-1b75-47e4-8c73-e698126c94b1/pdf"}