{"id":"c05f80fa-8cd1-4314-a1ab-b371731a6bd4","slug":"management-of-cerebrospinal-fluid-rhinorrhea-as-a-rare-complication-of-antiphospholipid-syndrome","title":"Management of cerebrospinal fluid rhinorrhea as a rare complication of antiphospholipid syndrome","authors":["Elissa Xian","Joel Hardman","Geoffrey Parker","Arjuna Nirmalananda"],"abstract":"Background: Antiphospholipid syndrome is a complex autoimmune condition associated with the formation of recurrent thrombosis in any vascular bed throughout the body. Jugular vein thrombosis is very rare with only a 0.9% occurrence and is not typically associated with cerebrospinal rhinorrhea as a result of raised intracranial pressure. Case Description: A 54-year-old patient presented with a 9-month history of cerebrospinal fluid (CSF) rhinorrhea and headache on a background of antiphospholipid syndrome. Investigations showed a superior vena cava (SVC) and right internal jugular vein (IJV) obstruction with moderately elevated intracranial venous pressures. Her magnetic resonance imaging (MRI) brain was consistent with a CSF leak. The patient underwent successful endovascular stenting of her obstructed SVC and right IJV followed by surgical repair of a herniating meningocele in the posterior left ethmoid air cells. Conclusion: CSF rhinorrhea is uncommon and never previously reported associated with SVC thrombosis induced by antiphospholipid syndrome. A combination of endovascular techniques and surgical repair is recommended for this challenging presentation.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/c05f80fa-8cd1-4314-a1ab-b371731a6bd4/featured/hero-1781559704424.png","publishDate":"2024-03-01T00:00:00.000Z","doi":"10.25259/SNI_32_2023","categories":["Unique Case Observations","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2024/03/12783/SNI-15-61.pdf"}