{"id":"de5ca534-18a0-48d8-9f2e-5ec52c74e05d","slug":"navigation-guided-endoscopic-biopsy-for-pathological-diagnosis-for-intraparenchymal-pure-germinoma-near-the-ventricular-trigone","title":"Navigation-guided endoscopic biopsy for pathological diagnosis for intraparenchymal pure germinoma near the ventricular trigone","authors":["Kuniyuki Onuma","Eiichi Ishikawa","Masahide Matsuda","Yasushi Shibata","Kaishi Satomi","Tetsuya Yamamoto","Alexander Zaboronok","Shingo Takano","Akira Matsumura"],"abstract":"Background: The authors report a case of intraparenchymal germinoma pathologically diagnosed using navigation-guided endoscopic biopsy. Case Description: A 27-year-old man had mild left hemiparesis, transcortical motor aphasia, and amnesia. Magnetic resonance (MR) imaging revealed an intraparenchymal mass lesion near the left ventricular trigone. Navigation-guided endoscopic biopsy was performed, and histopathology revealed large neoplastic cells immunohistochemically positive for germinoma-specific antigens, which were diagnosed as pure germinoma. Chemotherapy with whole-brain radiotherapy was performed, and the neurological symptoms did not change during the treatment. Follow-up MR imaging 1 year after the surgery showed no evidence of recurrence or dissemination. Conclusions: Navigation-guided endoscopic biopsy can be a useful technique in such intraparenchymal germinoma cases.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/de5ca534-18a0-48d8-9f2e-5ec52c74e05d/featured/hero-1782420843049.png","publishDate":"2012-01-21T00:00:00.000Z","doi":"10.4103/2152-7806.92177","categories":["Original Article"],"fullTextUrl":"https://surgicalneurologyint.com/api/articles/de5ca534-18a0-48d8-9f2e-5ec52c74e05d/pdf"}