{"id":"99519db5-fdcc-4927-9142-f36e31fee429","slug":"outcome-of-diffuse-axonal-injury-in-moderate-and-severe-traumatic-brain-injury","title":"Outcome of diffuse axonal injury in moderate and severe traumatic brain injury","authors":["Farrukh Javeed","Lal Rehman","Ali Afzal","Asad Abbas"],"abstract":"Background: Diffuse axonal injury (DAI) is a common presentation in neurotrauma. Prognosis is variable but can be dependent on the initial presentation of the patient. In our study, we evaluated the outcome of diffuse axonal injury. Methods: This study was conducted at a tertiary care center from September 2018 to December 2019 and included 133 adult patients with moderate or severe head injury (GCS ≤ 12) diagnosed to have the DAI on the basis of MRI. At 3 months, the result was assessed using the Extended Glasgow Outcome Scale (GOS-E). Results: There were a total of 97 (72.9%) males and 36 (27.1%) females with an average age of 32.4 ± 10 years with a mean GCS of 9 at admission. The most common mode of head trauma was road traffic accidents (RTAs) in 51.9% of patients followed by fall from height in 27.1%. Most patients were admitted with moderate traumatic brain injury (64.7%) and suffered Grade I diffuse axonal injury (41.4%). The average hospital stay was 9 days but majority of patients stayed in hospital for ≤ 11 days. At 3 months, mortality rate was 25.6% and satisfactory outcome observed in 48.1% of patients. The highest mortality was observed in the Grade III DAI. Conclusion: We conclude that the severity of the traumatic head injury and the grade of the DAI impact the outcome. Survivors require long-term hospitalization and rehabilitation to improve their chances of recovery.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/99519db5-fdcc-4927-9142-f36e31fee429/featured/hero-1781562160235.png","publishDate":"2021-08-03T00:00:00.000Z","doi":"10.25259/SNI_573_2020","categories":["Trauma","Original Article"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2021/08/11020/SNI-12-384.pdf"}