{"id":"74b3e0b4-561d-4a1a-ab43-2047ec9845ef","slug":"outcomes-using-linear-accelerator-stereotactic-radiosurgery-for-the-treatment-of-trigeminal-neuralgia-a-single-center-retrospective-study","title":"Outcomes using linear accelerator stereotactic radiosurgery for the treatment of trigeminal neuralgia: A single-center, retrospective study","authors":["Bornali Kundu","Andrea A. Brock","Jason G. Garry","Randy L. Jensen","Lindsay M. Burt","Donald M. Cannon","Dennis C. Shrieve","John D. Rolston"],"abstract":"Background: Linear accelerator (LINAC)-based stereotactic radiosurgery (SRS) treatment of trigeminal neuralgia (TN) may have similar efficacy to Gamma Knife SRS (GK-SRS), but the preponderance of data comes from patients treated with GK-SRS. Our objective was to analyze the outcomes for LINAC-based treatment of TN in patients at our institution. Methods: We retrospectively analyzed data for patients who underwent LINAC-based SRS for TN from 2006 to 2018. Data were collected from the patients’ medical records. Nonparametric statistics were used for the analysis. Results: Of the 41 patients treated with LINAC-based SRS (typically 90 Gy dosed using a 4 mm collimator for one fraction) during that time, follow-up data of >3 weeks post-SRS were available for 32 patients. The median pretreatment Barrow Neurological Institute (BNI) pain score was 5 (range 4–5). The follow-up period ranged from 0.9 to 113.2 months (median 5 months). There was significant improvement in postradiation BNI pain score (P 3). Survival analysis showed a median time to pain recurrence of 30 months. There was no relationship between prior microvascular decompression (MVD) surgery and change in BNI pain score pre- to posttreatment. Conclusion: The results demonstrate that LINAC-based SRS is an effective means to treat TN. Prior MVD surgery did not affect efficacy of SRS in lowering the BNI score from pre- to posttreatment in this patient cohort.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/74b3e0b4-561d-4a1a-ab43-2047ec9845ef/featured/hero-1781561279827.png","publishDate":"2022-06-10T00:00:00.000Z","doi":"10.25259/SNI_91_2022","categories":["Stereotactic","Original Article"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2022/06/11645/SNI-13-246.pdf"}