{"id":"9e8fe177-2f12-4eb7-acdb-40d209bdabfb","slug":"paraneoplastic-symptoms-caused-by-extracranial-meningioma-metastases","title":"Paraneoplastic symptoms caused by extracranial meningioma metastases?","authors":["Thomas Mindermann"],"abstract":"Background: There are only few reports on distant metastases of cranial meningiomas WHO I. In one-third of the cases, distant metastases seem to be clinically silent. This is the first case of distant metastases which may have manifested with a paraneoplastic syndrome. Case Description: A 52-year-old white male patient was diagnosed with distant metastases to the bones and liver 11 and 12 years following craniotomy and removal of a tentorial meningioma WHO I. At that time, the patient had developed paresthesia, unsteady gait, and a slight cognitive impairment, which in retrospect had no other explanation than that of a paraneoplastic syndrome. Eighteen years following craniotomy, a small intracranial tumor rest is under control following two single session radiosurgery treatments. At present, the patient has a multitude of bone and liver metastases, which seem to cause his paraneoplastic symptoms. Conclusion: Screening for malignancies in patients with paraneoplastic symptoms and a history of cranial meningioma should include screening for distant metastases from the meningioma.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/9e8fe177-2f12-4eb7-acdb-40d209bdabfb/featured/hero-1782420891237.png","publishDate":"2016-12-20T00:00:00.000Z","doi":"10.4103/2152-7806.196238","categories":["Case Report"],"fullTextUrl":"http://surgicalneurologyint.com/wp-content/uploads/2017/01/8243/SNI-7-106.pdf"}