{"id":"74dc91f4-96ff-4cbb-80b5-9fa9de89048f","slug":"postoperative-meningitis-due-to-carbapenemase-producing-klebsiella-pneumoniae-a-case-report-and-literature-review","title":"Postoperative meningitis due to carbapenemase-producing <i>Klebsiella pneumoniae</i>: A case report and literature review","authors":["Firas Kalai","Lotfi Rebai","Sarra Sammari","Olfa Faten","Sabrine Ben Brahem","Hichem Hadj Kacem","Ichraf Ardhaoui"],"abstract":"Background: Postoperative meningitis is a serious complication in neurosurgery. Early diagnosis and appropriate management are essential to reduce its significant morbidity and mortality. Case Description: We report the case of a 76-year-old patient who underwent evacuation of a posterior fossa hematoma. On postoperative day 19, he presented with fever and surgical wound necrosis. Surgical revision revealed a collection fistulized to the skin. Cerebrospinal fluid analysis and intraoperative samples confirmed postoperative meningitis caused by multidrug-resistant Klebsiella pneumoniae, susceptible only to colistin and fosfomycin. Despite treatment adjustment, the patient’s condition worsened, and he died 12 days after surgical revision due to massive pulmonary embolism. Conclusion: This case highlights the severity of postoperative meningitis due to extensively drug-resistant K. pneumoniae and underlines the importance of early diagnosis, bacteriological analysis of surgical samples, and rapid adaptation of antibiotic therapy in specialized settings.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/74dc91f4-96ff-4cbb-80b5-9fa9de89048f/featured/hero-1781558108631.png","publishDate":"2025-12-12T00:00:00.000Z","doi":"10.25259/SNI_752_2025","categories":["Infection","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2025/12/14143/SNI-16-519.pdf"}