{"id":"9b8aed3b-fbb4-421b-939a-65f46d9c136c","slug":"prediction-of-30-day-mortality-in-spontaneous-cerebellar-hemorrhage","title":"Prediction of 30-day mortality in spontaneous cerebellar hemorrhage","authors":["Diaa Al Safatli","Albrecht Guenther","Aaron Lawson McLean","Albrecht Waschke","Rolf Kalff","Christian Ewald"],"abstract":"Background: Cerebellar hemorrhage is a potentially life-threatening condition and an understanding of the factors influencing outcome is essential for sound clinical decision-making. Methods: We retrospectively evaluated data from 50 consecutive patients who suffered a first spontaneous cerebellar hemorrhage (SCH) from 2005 to 2014, analysing their short-term outcomes and identifying possible clinical, radiological and therapeutic risk factors for poor prognosis and death within 30 days. Results: Among 50 patients with first SCH, the mean age was 72 ± 10 years. Median Glasgow Coma Scale (GCS) score on admission was 11 [interquartile range (IQR) = 7–11]. Among 50 patients, 19 patients (38%) underwent surgical hemorrhage evacuation with placement of an external ventricular drain (EVD), 12 patients (24%) received an EVD only and 19 patients (38%) were treated conservatively. The 30-day mortality rate was 36%. In multivariate analysis only the GCS score on admission was a significant predictor of 30-day mortality [odds ratio (OR) = 0.598; 95% confidence interval (CI) = 0.406–0.879; P = 0.009]. For prediction of 30-day mortality, receiver operating characteristic curve analysis confirmed that the best cut-off point was a GCS score of 10 on admission [area under the curve: 0.882, 95% CI = 0.717–1, P < 0.001]. Conclusion: Lower GCS score on admission was associated with increased 30-day mortality and poorer short-term outcome in patients with SCH. For patients with a GCS score <10 on admission, it is important to balance the possibility of survival afforded by further therapy against the formidable risk of significant functional disability and poor quality of life.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/9b8aed3b-fbb4-421b-939a-65f46d9c136c/featured/hero-1782420889750.png","publishDate":"2017-11-20T00:00:00.000Z","doi":"10.4103/sni.sni_479_16","categories":["General Neurosurgery","Original Article"],"fullTextUrl":"http://surgicalneurologyint.com/wp-content/uploads/2017/11/8679/SNI-8-282.pdf"}