{"id":"591477fb-f633-495d-93d6-e4c24de38893","slug":"predictors-of-inpatient-complications-and-outcomes-following-surgical-resection-of-hypothalamic-hamartomas","title":"Predictors of inpatient complications and outcomes following surgical resection of hypothalamic hamartomas","authors":["Debraj Mukherjee","Christine Carico","Miriam Nuño","Chirag G Patil"],"abstract":"Background: Our aim was to identify the preoperative factors associated with a greater risk of poor inpatient outcomes in those undergoing resection of hypothalamic hamartomas. Methods: We performed a multi-institutional retrospective cohort analysis via the Nationwide Inpatient Sample (1998 – 2007). Patients of any age who underwent resection of hypothalamic hamartomas were identified by ICD-9 coding. The primary outcomes included inpatient complications, length of stay (LOS), and total charges. Multivariate regression models were constructed to analyze the outcomes. Results: Two hundred and eighty-two patients were identified with a mean age of 27.7 years, with most being male (53.2%), Caucasian (78.9%), privately insured (69.3%), and treated electively (74.7%) at academic centers (91.7%). A majority (82.2%) had Elixhauser comorbidity scores of P = 0.045) and academic hospitals (OR: 1.43, P = 0.008) were associated with significantly higher odds of any complication. Minority race / ethnicity was associated with a minimal increase in the odds of postoperative stroke (OR: 1.02, P < 0.001) relative to Caucasians. Conclusions: Through an analysis of a 10-year multi-institutional database, we have described the surgical outcomes of patients undergoing resection of hypothalamic hamartomas. Results demonstrate significant inpatient morbidity, particularly postoperative stroke. Patient- and institution-level factors should be considered in determining the perioperative risk for such patients.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/591477fb-f633-495d-93d6-e4c24de38893/featured/hero-1782421052816.png","publishDate":"2011-07-30T00:00:00.000Z","doi":"10.4103/2152-7806.83387","categories":["Original Article"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2015/05/3510/SNI-2-105.pdf"}