{"id":"62ed661f-390a-4a3e-bf45-a9f3120826a0","slug":"preoperative-lymphocyte-percentage-and-neutrophil-lymphocyte-ratio-are-useful-predictors-of-30-day-postoperative-complications-after-lumbar-fusion","title":"Preoperative lymphocyte percentage and neutrophil-lymphocyte ratio are useful predictors of 30-day postoperative complications after lumbar fusion","authors":["Temidayo Osunronbi","Balint Borbas","Hiba Lusta","Agbolahan Sofela","Himanshu Sharma"],"abstract":"Background: Lymphocyte percentage/count, platelet-lymphocyte ratio (PLR), and neutrophil-lymphocyte ratio (NLR) have shown prognostic significance in patients with cancer, stroke, and following cardiac surgery. However, the utility of these blood parameters for assessing the 30-day postoperative risk for lumbar fusion complications has not been established. Methods: In this single-center-single-surgeon retrospective series, 77 consecutive patients underwent one- or two-level lumbar fusion. Lymphocyte percentage/count, PLR, and NLR were investigated as predictors of 30-day postoperative complications. Results: Ten of 77 patients had postoperative complications. A unit increase in NLR and lymphocyte percentage was significantly associated with a 23% increase and 7% decrease, respectively, in the odds of a complication occurring. Preoperative NLR ≥ 2.32 and lymphocyte percentage ≤ 29.5% significantly discriminated between the “complication” and “no-complication” groups. Conclusion: Patients with a preoperative lymphocyte percentage of ≤29.5% and/or NLR ≥2.32 should be closely monitored as high-risk groups susceptible to 30-day postoperative complications after lumbar fusion.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/62ed661f-390a-4a3e-bf45-a9f3120826a0/featured/hero-cropped-1781561451364.jpg","publishDate":"2022-04-15T00:00:00.000Z","doi":"10.25259/SNI_160_2022","categories":["Spine","Original Article"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2022/04/11538/SNI-13-145.pdf"}