{"id":"5c7017d5-42e2-456b-a657-e70fb9c9936d","slug":"recent-neuroscience-advances-of-interest-to-neurosurgeons-neurologists-and-neuroscientists-may-2010-2","title":"Recent neuroscience advances of interest to neurosurgeons, neurologists and neuroscientists — May 2010","authors":["James I. Ausman"],"abstract":"Background: Recent advances in neuroscience have highlighted the potential of using personal genomic data to predict and prevent diseases. Notably, studies have shown how genetic analysis can identify risks for conditions such as myocardial infarction and certain cancers, as well as inform treatment strategies for various disorders. Methods: This article reviews several key studies published in 2010 that explore the molecular mechanisms underlying conditions such as neurofibromatosis type 2, disc degeneration, malignant cerebral infarctions, and cerebral aneurysms. Each study employs different methodologies, including genetic analysis, gene therapy, and molecular treatments in animal models. Results: Findings indicate that genetic mutations can lead to tumor formation in neurofibromatosis type 2, while gene therapy using growth factors can regenerate degenerated discs. Additionally, the use of Glibenclamide has shown promise in reducing cerebral edema in stroke models, and a novel approach to aneurysm treatment using rhVEGF has demonstrated effective vessel occlusion. Conclusion: These studies represent significant strides in understanding and treating neurological conditions through molecular and genetic approaches. The integration of genomic data into clinical practice may lead to more personalized and effective treatment strategies for patients. Keywords: genomics, neurofibromatosis, gene therapy, cerebral infarction, aneurysm, molecular treatment, personalized medicine","thumbnailUrl":null,"publishDate":"2010-05-31T00:00:00.000Z","doi":"10.4103/2152-7806.63902","categories":["Original Article"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2015/05/3204/SNI-01-11.pdf"}