{"id":"b2e9f7f6-daf5-4af7-9b30-97e5b7215ea9","slug":"senile-thoracolumbar-tuberculosis-with-kyphosis-and-severe-osteoporosis-treated-with-polymethylmethacrylate-augmented-screw-fixation","title":"Senile thoracolumbar tuberculosis with kyphosis and severe osteoporosis treated with polymethylmethacrylate-augmented screw fixation","authors":["B. Yogesh Kumar","Bharath Loganathan","D. Vijayakumar"],"abstract":"Background: Elderly osteoporotic patients with kyphosis secondary to spinal tuberculosis (TB) are at high risk for implant failure. For these patients, polymethylmethacrylate (PMMA)-augmented pedicle screw fixation provides immediate stability but increases the risk of infection. Here, we evaluated the outcome for a 78-year-old osteoporotic female with TB-related kyphosis successfully managed with PMMA-augmented pedicle screw fusion. Case Description: A 78-year-old female presented with mid-back pain, progressive kyphotic deformity, and increasing paraparesis. The magnetic resonance imaging revealed infectious T12-L1 spondylitis with accompanying vertebral body destruction/kyphosis. She underwent a single-stage posterior PMMA-augmented screw fixation from T9-L4 supplemented with anterior reconstruction and cage/bone grafting. The histology/cultures were consistent with spinal TB for which she received anti-tuberculosis therapy, followed by once weekly teriparatide (60 µg for 6 weeks). Neurological recovery was complete within 3 months, and by 2 years, the imaging confirmed a stable fusion. Conclusion: A 78-year-old osteoporotic female with T12/L1 TB-related spondylitis successfully underwent selective PMMA-augmented pedicle screw fixation from T9-L4 supplemented with anti-tubercular therapy.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/b2e9f7f6-daf5-4af7-9b30-97e5b7215ea9/featured/hero-1781558068338.png","publishDate":"2025-12-26T00:00:00.000Z","doi":"10.25259/SNI_1140_2025","categories":["Spine","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2025/12/14189/SNI-16-552.pdf"}