{"id":"c146d55e-43bf-4fbb-b2b7-76eadfb05664","slug":"sni-17-444","title":"Atlantoaxial dislocation in a patient with Neurofibromatosis type 1: Case report and review","authors":["Abolfazl Rahimizadeh","Housain Soufiani","Khodakaram Rastegar","Abdolhadi Daneshi","Chia Peroutighalat","Mahan Amirzadeh","Naser Asgari"],"abstract":"Background: Neurofibromatosis type 1 (NF1) or von Recklinghausen’s disease is a complex multi-system genetic disorder characterized by neurocutaneous manifestations, nervous system affection, and various skeletal dysplasia. Rarely, this disorder might be associated with atlantoaxial dislocation (AAD). Case Description: A 65-year-old male with a prior diagnosis of (NF1) was referred due to progressive spastic quadriparesis. Dynamic cervical spine radiographs and magnetic resonance showed reducible AAD with cervicomedullary cord compression/myelopathy. Triple construct C1–C2 screw–rod–hook fixation results in steady postoperative neurological recovery. Conclusion: Here, we reviewed the clinical presentation, diagnostic challenges, and surgical fusion for C1–C2 instability in a 65-year-old male with type 1 (NF1) and cervicomedullary cord compression.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/sni-17-444/figures/SNI-17-444-g002.jpg","publishDate":"2026-08-07T00:00:00.000Z","doi":"10.25259/SNI_646_2026","categories":["Spine","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/api/articles/c146d55e-43bf-4fbb-b2b7-76eadfb05664/pdf"}