{"id":"ea6b150e-015c-4e81-9905-a6c3b3713301","slug":"sni-17-470","title":"Post-traumatic meningioma or coincidental occurrence? A case report and critical review of the literature","authors":["Antonello Curcio","Shervin Espahbodinea","Giovanni Raffa","Antonino Francesco Germanò"],"abstract":"Background: The possible causal relationship between traumatic brain injury and subsequent meningioma development remains controversial. Although historical and anecdotal reports have suggested a post-traumatic origin of meningiomas, robust epidemiological evidence is lacking, and the distinction between causality and coincidence remains challenging. Case Description: We report the case of a 78-year-old man who sustained a severe frontal cranial trauma with a comminuted fracture and retained foreign body 40 years earlier, treated surgically by craniectomy. Decades later, the patient presented with a headache and cognitive disturbance. Neuroimaging revealed a frontal meningioma arising beneath and within the previous craniectomy site. The tumor was successfully removed en bloc through navigated craniectomy, followed by dural reconstruction and cranioplasty. Histopathological examination confirmed a benign meningioma. The postoperative course was uneventful, and follow-up imaging showed no recurrence. Conclusion: Rather than supporting a traumatic origin of meningioma, this case underscores the limitations in attributing causality between head trauma and tumor development. It emphasizes the need for cautious interpretation of post-traumatic tumor cases and provides clinically relevant insights into the evaluation of meningioma etiology.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/sni-17-470/figures/SNI-17-470-g001.jpg","publishDate":"2026-08-21T00:00:00.000Z","doi":"10.25259/SNI_1127_2025","categories":["Neuro-oncology","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/api/articles/ea6b150e-015c-4e81-9905-a6c3b3713301/pdf"}