{"id":"d7dd4cd3-d997-4f53-9571-476678148536","slug":"solitary-fibrous-tumor-hemangiopericytoma-of-the-cervical-spine-a-systematic-review-of-the-literature-with-an-illustrative-case","title":"Solitary fibrous tumor/hemangiopericytoma of the cervical spine: A systematic review of the literature with an illustrative case","authors":["Antonio Colamaria","Francesco Carbone","Matteo Sacco","Fabrizio Corsi","Augusto Leone","Giovanni Parbonetti","Matteo de Notaris","Nicola Pio Fochi","Matteo Landriscina","Giulia Coppola","Elena de Santis","Guido Giordano"],"abstract":"Background: In the WHO 2016 classification of central nervous system tumors, solitary fibrous tumors (SFT) and hemangiopericytomas (HPC) were considered part of the same category given a shared mutation. Nevertheless, since the new 2021 WHO classification, the term “hemangiopericytoma” has been retired, and SFT is considered an independent pathological entity. Methods: We reviewed the literature following preferred reporting items for systematic reviews and meta-analyses guidelines focusing on the treatment options and prognosis of patients with cervical SFT. We also present a 68-year-old female with spinal intradural extramedullary SFT complicated by diffuse extension into paravertebral tissues and muscles. Results: We found 38 cervical SFT in the literature. Patients averaged 47.3 years of age and 47.4% were female. Typically, these lesions spanned two spinal levels resulting in cord compression and most frequently exhibited benign features (i.e., diagnosed as Grade I SFTs). Interestingly, two patients exhibited distant metastases and had initial pathology consistent with grade II SFT. Conclusion: SFT of the cervical spine is rare and its management varies according to the histological grade and the clinical behavior, generally warranting surgical excision and adjuvant radiation therapy and/or systemic chemotherapy.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/d7dd4cd3-d997-4f53-9571-476678148536/featured/hero-1781560716512.png","publishDate":"2022-11-18T00:00:00.000Z","doi":"10.25259/SNI_722_2022","categories":["Neuro-oncology","Review Article"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2022/11/12014/SNI-13-532.pdf"}