{"id":"d66aa0ca-bdf8-417b-8e40-c6d1e5a97fef","slug":"stereotactic-biopsy-of-a-brain-lesion-caused-by-hormographiella-aspergillata","title":"Stereotactic biopsy of a brain lesion caused by <i>hormographiella aspergillata</i>","authors":["F. H. Hounchonou","Joachim Runge","Arnold Ganser","Christian Hartmann","Peter Raab","Joachim K. Krauss"],"abstract":"Background: Invasive fungal infections are an increasing problem in immunosuppressed patients. In patients with the central nervous system involvement, there is a high case fatality rate. There is a very limited experience with infections caused by Hormographiella aspergillata (HA) in such cases and most often diagnosis is only confirmed postmortem. Case Description: We report the case of a 53-year-old woman with acute myeloid leukemia. After primary therapy with daunorubicin, cytarabine, and gemtuzumab ozogamicin, the patient developed pneumonia and later neurological symptoms caused by multiple gadolinium-enhancing brain lesions in magnetic resonance imaging (MRI). Stereotactic biopsy of a frontal precentral lesion was performed and revealed HA infection. The patient died in the further course secondary to cardiopulmonary problems. Conclusion: Stereotactic biopsy is a safe way to establish the diagnosis of unclear lesions such as HA infection. We recommend to perform stereotactic biopsy early in immunocompromised patients with brain lesions to guide further treatment.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/d66aa0ca-bdf8-417b-8e40-c6d1e5a97fef/featured/hero-1781560612983.png","publishDate":"2022-12-30T00:00:00.000Z","doi":"10.25259/SNI_576_2022","categories":["Stereotactic","Case Report"],"fullTextUrl":"https://surgicalneurologyint.com/api/articles/d66aa0ca-bdf8-417b-8e40-c6d1e5a97fef/pdf"}