{"id":"5da6f889-5362-40b3-8880-702fd1304a9c","slug":"the-effect-of-weight-in-the-outcomes-of-meningioma-patients","title":"The effect of weight in the outcomes of meningioma patients","authors":["Holly Dickinson","Christine Carico","Miriam Nuño","Kristin Nosova","Adam Elramsisy","Chirag G. Patil"],"abstract":"Background: Meningiomas are more prevalent in women and mostly benign in nature. Our aim was to evaluate the association of weight and outcomes of meningioma patients undergoing craniotomy. Methods: A retrospective analysis of meningioma patients discharged postcraniotomy between 1998 and 2007 was conducted. Univariate and multivariate analysis evaluated in-hospital mortality, complications, length of stay (LOS), and cost. Results: According to the nationwide inpatient sample (NIS) database, an estimated 72,257 adult meningioma patients underwent a craniotomy in US hospitals during the study period. Female and male weight loss rates were 0.7% and 1.2%, respectively; obesity rates were 5.2% and 3.7%. Males had higher rates of malignant tumors than females (6.2% vs. 3.5%, P P = 0.03). Weight loss was associated with higher mortality in men (OR 6.66, P P = 0.04) as well as higher rates of postoperative complications in both men (OR 6.13, P P P = 0.0006) and complications (OR 0.8, P = 0.0007) among women. Conclusions: In summary, weight loss seems to be the single most critical factor present in patients experiencing higher mortality, complications, hospital charges, and longer LOS. However, further studies aimed to assess the inter-relation of potential preexisting comorbidities and weight loss are needed to establish causation.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/5da6f889-5362-40b3-8880-702fd1304a9c/featured/hero-1782420858393.png","publishDate":"2013-04-03T00:00:00.000Z","doi":"10.4103/2152-7806.110023","categories":["Original Article"],"fullTextUrl":"http://sni.wpengine.com/wp-content/uploads/2015/05/3696/SNI-4-45.pdf"}