{"id":"ffd96bfd-655e-4ce4-9b2e-38cacc3651d3","slug":"the-extended-endoscopic-endonasal-approach-for-the-removal-of-a-mixed-intrasuprasellar-germinoma-technical-case-report-2","title":"The “extended” endoscopic endonasal approach for the removal of a mixed intrasuprasellar germinoma: Technical case report","authors":["Alberto Di Somma","Carolina Bronzoni","Elia Guadagno","Domenico Solari","Giovanni Orabona Dell’Aversana","B. S. Marialaura Del Basso De Caro","Paolo Cappabianca"],"abstract":"Background: Intracranial germ cell tumors (GCTs) represent less than 5% of pediatric brain tumors. Neurosurgical treatment remains essential in the management of patients with intracranial nongerminomatous GCT. Case Description: A 12-year-old girl presented with clinical features of neurohypophyseal dysfunction and rapidly progressive visual worsening. Magnetic resonance imaging (MRI) showed a lesion arising from the sella with a significant suprasellar component, compressing the optic chiasm and extending into the third ventricle. The tumor was removed via an endoscopic endonasal transtuberculum-transplanum approach and the histology revealed a mixed germinoma. In the postoperative course, a conspicuous improvement of visual function was observed; an early postoperative MRI showed near-total removal of the lesion. The patient was referred to pediatric oncologist for the adjunctive chemotherapy and radiotherapy. Conclusions: The management of primary intracranial sellar and suprasellar germinomas still remains controversial. With this report we highlighted another possible surgical option among therapeutic strategies for these highly malignant tumors.","thumbnailUrl":"https://sni-digital-videos.s3.amazonaws.com/articles/ffd96bfd-655e-4ce4-9b2e-38cacc3651d3/featured/hero-1782421009933.png","publishDate":"2014-01-29T00:00:00.000Z","doi":"10.4103/2152-7806.126043","categories":["Original Article"],"fullTextUrl":"https://surgicalneurologyint.com/wp-content/uploads/2015/03/3628/SNI-5-14.pdf"}