{"id":"9b7d99b9-98c9-4931-9414-a7a39ef3aa27","slug":"trigeminocardiac-reflex-some-thought-to-the-definition-response","title":"Trigeminocardiac reflex: Some thought to the definition, response","authors":["A. Amirjamshidi","F. Etezadi"],"abstract":"Background: The trigeminocardiac reflex (TCR) is characterized by four components: bradycardia, hypotension, apnea, and gastric hypermotility. This study focuses on two hemodynamic variables to define TCR, excluding apnea and gastric hypermotility due to methodological limitations. The occurrence of gastric hypermotility in humans has not been substantiated in prior research. Methods: The study involved 190 cases across various surgical procedures, ensuring a controlled level of general anesthesia to mitigate confounding factors. The researchers aimed to establish a clinically meaningful cut-off point for TCR, defined as a 20% change in hemodynamic variables. The study design was informed by previous literature to avoid common methodological pitfalls. Results: The findings indicate that TCR is prevalent during neurosurgical procedures, particularly when anesthesia is not sufficiently deep. The study supports the notion that the level of surgical aggression and patient pain perception significantly influences the magnitude of autonomic reflexes, including TCR. Conclusion: While the TCR is a well-documented reflex, its occurrence can be minimized through adequate anesthesia depth. Future research should focus on animal studies to better understand the cause-effect relationships associated with TCR, as human studies face ethical limitations. Keywords: trigeminocardiac reflex, TCR, bradycardia, hypotension, anesthesia, neurosurgery, autonomic reflexes","thumbnailUrl":null,"publishDate":"2014-07-29T00:00:00.000Z","doi":"10.4103/2152-7806.137725","categories":["Original Article"],"fullTextUrl":"https://surgicalneurologyint.com/api/articles/9b7d99b9-98c9-4931-9414-a7a39ef3aa27/pdf"}