- Department of Neurosurgery, Mayo Clinic, Scottsdale, Arizona, United States.
DOI:10.25259/SNI_92_2021Copyright: © 2021 Surgical Neurology International This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
How to cite this article: Rohin Singh, Maziyar Kalani. Cervical intradural intramedullary collision tumor of schwannoma and hemangioblastoma origin. 14-Apr-2021;12:155
How to cite this URL: Rohin Singh, Maziyar Kalani. Cervical intradural intramedullary collision tumor of schwannoma and hemangioblastoma origin. 14-Apr-2021;12:155. Available from: https://surgicalneurologyint.com/?post_type=surgicalint_articles&p=10721
Background: Primary spinal tumors are rare benign lesions that represent around 2–4% of all central nervous system neoplasms.[
Case Description: A 61-year-old female presented with a 2-year history of the right arm numbness, weakness, and tingling. She reported some lower extremity numbness but an otherwise normal neurological examination. She had a prior carpal tunnel release that did not alleviate her symptoms. Noncontrast MRI of the cervical spine demonstrated a holocord syrinx from C2 to C7 and spondylolisthesis from C4 to C5. MRI with contrast then displayed an enhancing nodule behind the vertebral body of C4. A standard posterior approach and subperiosteal dissection were performed. Lateral mass screws were placed at C3-C5, and the laminectomy was performed en bloc. Intraoperative ultrasound was used to locate the lesion, and intraoperative dorsal column mapping was used to identify the midline before performing a midline myelotomy. The arachnoid over the lesion was opened and an extracapsular dissection was performed. Hemostasis was obtained, and a watertight dural closure was performed.
Conclusion: The patient tolerated the procedure well and achieved relief from cervical myelopathy symptoms. Pathology indicated positive biomarkers for S-100, SOX10, and NSE indicating a schwannoma hemangioblastoma collision tumor. This is unusual in its nature given two benign lesions with differing underlying cell types of origin.
Keywords: Collision tumor, Hemangioblastoma, Intradural intramedullary, Schwannoma, Spinal tumor
0:32 – Pre-operative imaging findings. 1:17 – Risks and benefits of procedure. 3:01 – Operation. 4:54 – Disease background. 5:30 – Post-operative imaging findings.
0:32 – Pre-operative imaging findings.
1:17 – Risks and benefits of procedure.
3:01 – Operation.
4:54 – Disease background.
5:30 – Post-operative imaging findings.
1. Caro-Osorio E, Herrera-Castro JC, Barbosa-Quintana A, Benvenutti-Regato M. Primary Spinal cord small-cell glioblastoma: Case report and literature review. World Neurosurg. 2018. 118: 69-70
2. Grimm S, Chamberlain MC. Adult primary spinal cord tumors. Expert Rev Neurother. 2009. 9: 1487-95