- Department of Pathology, Guntur Medical College, Guntur, Andhra Pradesh, India
- Department of Neurosurgery, Government General Hospital, Guntur, Andhra Pradesh, India
Renuka Inuganti Venkata
Department of Pathology, Guntur Medical College, Guntur, Andhra Pradesh, India
DOI:10.4103/2152-7806.84242Copyright: © 2011 Venkata RI. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
How to cite this article: Venkata RI, Kakarala SV, Garikaparthi S, Duttaluru SS, Parvatala A, Chinnam A. Giant intracranial osteochondroma: A case report and review of the literature. Surg Neurol Int 30-Aug-2011;2:118
How to cite this URL: Venkata RI, Kakarala SV, Garikaparthi S, Duttaluru SS, Parvatala A, Chinnam A. Giant intracranial osteochondroma: A case report and review of the literature. Surg Neurol Int 30-Aug-2011;2:118. Available from: http://sni.wpengine.com/surgicalint_articles/giant-intracranial-osteochondroma-a-case-report-and-review-of-the-literature/
Background:Intracranial osteochondromas are uncommon. The majority of lesions arise from the base of the skull or from bones developed by endochondral ossification. A minority of cases are attached to the falxcerebri in the fronto parietal location.
Case Description:We report a case of a giant intracranial osteochondroma in a 24-year-old man. This patient presented with complaints of convulsions and headache. Imaging studies of the brain, gross, and histological features concluded it to be an osteochondroma.
Conclusion:This case is reported in view of extreme rarity of the lesion, and to emphasize the fact that complete surgical resection is curative.
Keywords: Falxcerebri, intracranial, osteochondroma
Intracranial osteochondromas represent 0.1-0.2% of all intracranial tumors.[
A 24-year-old man was admitted with a history of convulsions since 3 months and episodes of headache since 2 months. Neurological examination was unremarkable. Preoperative computed tomography of the brain showed a mixed density mass of size 7 × 6 cm with calcifications in the right frontal lobe. Differential diagnoses offered were oligodendroglioma and meningioma. Magnetic resonance imaging showed a heterogeneous mass lesion of size 5.5 × 4.5 cm in the right frontal lobe with tiny hypo intense foci [
On opening the dura, a hard, glistening white smooth-surfaced irregular mass was seen in the right frontal region, with minimal attachment to the dura; the mass was resected enbloc [
An ivory hard lobulated gray blue translucent mass measuring 7 × 7 × 3.5 cm was received. The cut section of the tumor showed a cartilaginous cap with underlying hard bone [
Osteochondroma, also known as exostosis, is a benign cartilage capped tumor that originates on the surface of bones. They are commonly seen in long tubular bones such as the distal femur, proximal tibia, and proximal humerus. Intracranial osteochondromas are rare, if seen; the majority arise from the base of the skull. Very few cases arise from the dura attached to the falx cerebri in the fronto parietal location as in the present case. Extra skeletal osteochondromas originate from nonskeletal or noncartilaginous tissue. Intracranial osteochondromas are solitary but few cases occur as components of generalized mesenchymal neoplasias including Maffuci's and Ollier's disease. These tumors are seen as a result of defective endochondral ossification.
Intracranial osteochondromas arise at any age with a predilection for younger individuals. Tumor grows slowly over many years and can attain a very large size without clinical symptoms, especially when supratentorial. Tumors arising from the base of the skull present earlier. They have also been reported to arise from cranial nerves,[
The main pathological differential diagnosis was low grade chondrosarcoma, which was ruled out in the present case by the absence of cellular pleomorphism, nuclear atypia, and binucleate chondrocytes. An extensive skeletal survey of the patient and past clinical history ruled out the possibility of a secondary deposit from a low-grade chondrosarcoma.
Complete surgical excision is curative.[
This case is reported in view of extreme rarity of the lesion, and to emphasize the fact that complete surgical resection is curative.
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