Posterior resection of sacral osteosarcoma utilizing cement-infused chest tube interbody reconstruction and lumbopelvic fusion
- Department of Neurosurgery, Rutgers University, Newark, United States.
- Department of Orthopaedic Surgery, Rutgers-Robert Wood Johnson University Hospital, New Brunswick, New Jersey, United States.
- Department of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, United States.
Amanda M. Carpenter, Department of Neurosurgery, Rutgers University, Newark, New Jersey, United States.
DOI:10.25259/SNI_902_2021Copyright: © 2021 Surgical Neurology International This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
How to cite this article: Amanda M. Carpenter1, M. Omar Iqbal1, Neil Majmundar1, Gino Chiappetta2, Shabbar Danish1, Volker Sonntag3. Posterior resection of sacral osteosarcoma utilizing cement-infused chest tube interbody reconstruction and lumbopelvic fusion. 08-Dec-2021;12:599
How to cite this URL: Amanda M. Carpenter1, M. Omar Iqbal1, Neil Majmundar1, Gino Chiappetta2, Shabbar Danish1, Volker Sonntag3. Posterior resection of sacral osteosarcoma utilizing cement-infused chest tube interbody reconstruction and lumbopelvic fusion. 08-Dec-2021;12:599. Available from: https://surgicalneurologyint.com/surgicalint-articles/11274/
Background: Primary osteosarcoma (OS) of the spine is very rare. En bloc resection of spinal OS is challenging due to anatomical constraints. Surgical planning must balance the benefits of en bloc resection with its potential risks of causing a significant neurological deficit. In this case, we successfully performed a posterior-only approach for decompression with S1 reconstruction via a cement-infused chest tube interbody device, along with a navigated L4 to pelvis fusion.
Case Description: A 49-year-old female presented with a primary sacral OS. Computed tomography (CT) and magnetic resonance (MR) imaging revealed an S1 lytic vertebral body lesion with severe stenosis and progressive L5 on S1 anterior subluxation. Surgical decompression with tumor resection and S1 corpectomy with S1 reconstruction via a cement-infused 32-French chest tube interbody device accompanied by L4 -pelvis fusion utilizing S2-alar-iliac screws was completed. 6 months postoperatively, the patient continues to have significant pain relief and the instrumentation remains intact.
Conclusion: A 49-year-old female with an S1 OS successfully underwent a posterior-only approach that included an S1 corpectomy with anterior column reconstruction via a cement-infused chest tube interbody plus a navigated L4 to pelvis fusion.
Keywords: Osteosarcoma, Pelvic fixation, Spine oncology
Primary osteosarcomas (OSs) of the spine is very rare. En bloc resection of OS of the spine is challenging due to anatomical constraints of nearby critical structures. Standard of care for OS is neoadjuvant chemotherapy followed by surgery for en bloc tumor resection with wide margins, and adjuvant chemotherapy.[
The patient is a 49-year-old female who presented with 6 weeks of severe low back pain and left-sided radiculopathy with focal bilateral S1 numbness on neurological exam. Her lower extremities exhibited full strength.
Magnetic resonance (MR) and computed tomography (CT) diagnostic workup
The lumbosacral MR imaging (MRI) with and without contrast revealed small enhancing lesions in the vertebral bodies of T3, T12, L2, and L3, and a large enhancing lesion of the S1 body with epidural extension causing central canal stenosis and compression of both descending S1 nerve roots [
Due to the increased pain, the patient was placed on multiple medications including intrathecal opioids, without any relief. At this point, we felt that resection of the mass followed by stabilization would improve the patient’s pain, improve her function, as well as reduce her tumor burden.
An L4 to sacroiliac instrumented fusion with bilateral transpedicular sacral tumor debulking and S1 reconstruction with a cement-infused chest tube interbody prosthesis was planned.
Using navigation assistance, pedicle screws were placed bilaterally at L4 and L5, along with two S2-alar-iliac (S2AI) screws on each side. The tumor was readily identified and resected easily with suction. We then measured 24 mm between the inferior endplate of L5 and the superior endplate of S2 from the repeat intraoperative CT obtained after screw placement.
Unique 32-french tube interbody corpectomy construct
A 32-French chest tube (10.7 mm diameter) was cut to span the L5 to S2 defect. Two small windows were cut on the lateral surface of the chest tube through which cement would be injected. Two small stab incisions were made, superiorly and inferiorly, lateral to the midline lumbar incision, to allow the cement infusion cannulas to be inserted and angled appropriately to engage in the holes made along the lateral surface of the chest tube. A temporary rod was placed between the left L5 and S2AI screws. Under c-arm fluoroscopy, the chest tube strut was inserted into the corpectomy defect, inferior to the right-sided L5 nerve root and lateral to the right-sided S1 nerve root. The chest tube fit nicely onto the S2 endplate which measured 18 mm in anterior-posterior dimension. The lateral cement cannulas were then inserted percutaneously, engaged in the lateral chest tube holes and cement was injected to fill the implant through the inferior hole. The cement filled the strut graft until appropriate contact at both endplates was achieved [
Intraoperative fluoroscopy images are shown in photos a, b, and c. Pedicle instrumentation is seen at L4 and L5, and S2-alar-iliac screws caudally. A chest tube is positioned between the inferior endplate of L5 and superior endplate of S2. Progressive cement injection into holes in the chest tube can be seen in a, b, and c, respectively, until the implant was filled and there was appropriate contact at both endplates. In d, a photo of the operative field demonstrates the three-rod construct, as well as the plastic tubing through which cement was injected.
Within 5 days, the patient was able to walk a few steps and had significant pain relief. On postoperative day 8, chemotherapy was initiated with cisplatin and doxorubicin. Six months postoperatively, the patient remains on chemotherapy, is neurologically intact, with a follow-up CT showing all hardware in good position without tumor recurrence.
Surgery remains the gold standard treatment in cases of spine instability and/or epidural tumor with spinal cord compression. The Spinal Instability Neoplastic Score is a tool to help determine stability in the setting of spine tumors.[
In this case, conservative management of the OS pain -- including the use of opiate infusions and intrathecal therapies -- were ineffective in managing our patient’s pain and rendered her bedbound. Laminectomy alone in our patient led to worsening of her pain likely secondary to increased instability and anterior subluxation following posterior element disruption. We performed a posterior-only approach to resect tumor, decompress the spinal canal, and provide fixation in the form of a unique cement-infused chest tube interbody and fusion from L4 to the pelvis.
To overcome the difficulty of placing an interbody device through a narrow corridor via a posterior approach, we utilized the technique of customized cement-infused chest tube interbody placement.[
OS of the S1 vertebral body can be safely managed with a posterior-only approach to accomplish tumor decompression and stabilization. In this case, we performed decompression and tumor resection followed by an S1 corpectomy and interbody placement of a unique cement-infused chest tube plus instrumentation from L4 to the pelvis.
Patient’s consent not required as patients identity is not disclosed or compromised.
There are no conflicts of interest.
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