Deformative stress associated with an abnormal clivo-axial angle: A finite element analysis

Fraser C. Henderson, William A. Wilson, Stephen Mott, Alexander Mark, Kristi Schmidt, Joel K. Berry, Alexander Vaccaro, Edward Benzel

Date of publication: 16-Jul-2010

Background:Chiari malformation, functional cranial settling and subtle forms of basilar invagination result in biomechanical neuraxial stress, manifested by bulbar symptoms, myelopathy and headache or neck pain. Finite element analysis is a means of predicting stress due to load, deformity and strain. The authors postulate linkage between finite element analysis (FEA)-predicted biomechanical neuraxial stress and metrics of neurological function.

Type 2 diabetes mellitus: A central nervous system etiology

Peter J. Jannetta, Lynn H. Fletcher, Peter M. Grondziowski, Kenneth F. Casey, Raymond F. Sekula Jr

Date of publication: 16-Jul-2010

Background:Insulin resistance (hyperinsulinemia) is said to be the signal event and causal in the development of type 2 diabetes mellitus. Pulsatile arterial compression of the right anterolateral medulla oblongata is associated with autonomic dysfunction, including “driving” the pancreas, which increases insulin resistance causing type 2 diabetes mellitus. In this prospective study, we hypothesize that decompressing the right cranial nerve X and medulla will result in better glycemic control in patients with type 2 diabetes mellitus.

Pulsatile arterial compression of cranial nerves

Joyce S. Nicholas, Sunil J. Patel

Date of publication: 16-Jul-2010

Perioperative fatal embolic cerebrovascular accident after radical prostatectomy

Ramsis F. Ghaly, Kenneth D. Candido, Nebojsa Nick Knezevic

Date of publication: 01-Jul-2010

Background:There is little written about the management of perioperative cerebrovascular accident (CVA). To the best of our knowledge, the present case report represents the first case in the literature of a well-documented intraoperative embolic CVA and perioperative mortality in a relatively healthy, young patient with no contributing comorbidity and no noteworthy intraoperative event.

Tension pneumocephalus as complication of burr-hole drainage of chronic subdural hematoma: A case report

Nissar Shaikh, Irfan Masood, Yolande Hanssens, André Louon, Abdel Hafiz

Date of publication: 06-Jul-2010

Background:Pneumocephalus is the presence of air in the cranial cavity. When this intracranial air causes increased intracranial pressure and leads to neurological deterioration, it is known as tension pneumocephalus (TP). TP can be a major life-threatening postoperative complication, especially after evacuation of chronic subdural hematoma. We report a case of TP after evacuation of chronic subdural hematoma and review the literature.

Transcranial approach to pituitary adenomas invading the cavernous sinus: A modification of the classical technique to be used in a low-technology environment

Aldo Spallone, Roberto V. Vidal, Justo G. Gonzales

Date of publication: 01-Jul-2010

Objective:Pituitary adenomas invading the cavernous sinus represent a therapeutic challenge. Those tumors have been traditionally treated with incomplete surgical removal, observation and/ or adjunctive medical therapy, and radiotherapy. In relatively recent years, some authors have suggested a main direct surgical approach to cavernous sinus (CS) with the aim of complete removal of the adenoma, either by a modified trans-sphenoidal route, using or not an endoscopy-assisted approach, or by a transcranial direct approach. The latter has the advantage of allowing direct exposure of the lesion with a view of the surgical field unhindered by important neurovascular structures.

In this issue of SNI — June 2010

James I Ausman

Date of publication: 01-Jul-2010